Evidence map›Paper›PMID 38874879›Full record

ArticleAdvances in therapy2024

APPaRENT 3: Asthma Patients' and Physicians' Perspectives on the Burden and Management of Asthma in Seven Countries.

Bhumika Aggarwal, Mohamed Al-Moamary, Riyad Allehebi, Ashraf Alzaabi, Mona Al-Ahmad, Muhammad Amin, Triya Damayanti, Nguyen Van Tho, Pham Thi Le Quyen, Thitiwat Sriprasart and 11 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Advances in therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06652542 (Asthma Exacerbations & Respiratory Management), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06652542 completednot on this map

Asthma Exacerbations & Respiratory Management: An International Online Survey Endorsed by the International Association of Non-invasive Ventilation & International College of Experts

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled93ConditionsAcute Asthma Exacerbations
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Inhaled Corticosteroid/Long-Acting βAdvances in therapy · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Bhumika AggarwalGeneral Medicines, GSK, 23 Rochester Park, #06-01, GSK Asia House, Singapore, 139234, Singapore. bhumika.x.aggarwal@gsk.com.
Mohamed Al-MoamaryDepartment of Medicine, College of Medicine, King Saudi Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.
Riyad AllehebiDepartment of Pulmonology, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
Ashraf AlzaabiInternal Medicine Department, College of Medicine and Health Sciences, UAE University, Abu Dhabi, United Arab Emirates.
Mona Al-AhmadMicrobiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Muhammad AminDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga Hospital, Surabaya, Indonesia.
Triya DamayantiDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital National Respiratory Center, Jakarta, Indonesia.
Nguyen Van ThoDepartment of Tuberculosis and Lung Diseases, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Pham Thi Le QuyenRespiratory Center, Bach Mai Hospital, Hanoi, Vietnam.
Thitiwat SriprasartDepartment of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Orapan PoachanukoonCenter of Excellence for Allergy, Asthma and Pulmonary Diseases and Department of Pediatrics, Thammasat University, Pathum Thani, Thailand.
Andrea Ban Yu-LinRespiratory Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Ahmad Izuanuddin IsmailFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia.
Maria Encarnita B LimpinPulmonary and Critical Care Medicine Division, Philippine Heart Center, Quezon City, Philippines.
Steven KoenigSt. Claire HealthCare, Morehead, KY, USA.
Gur LevyGSK, Panama City, Panama.
Abhay PhansalkarGSK, Mumbai, India.
Farouz RafihGSK, Dubai, United Arab Emirates.
Mark SilveyAdelphi Real World, Bollington, UK.
Laura MiriamsAdelphi Real World, Bollington, UK.
Gary MilliganAdelphi Real World, Bollington, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAsthma management is strongly dependent on physician and patient beliefs and perceptions about the disease and its long-term treatment. The APPaRENT 3 study was conducted to explore factors influencing treatment choice and to understand patients' and physicians' attitudes and perspectives on the use of controller inhalers in regular versus flexible dosing for asthma management.

methodsThis cross-sectional survey of patients with asthma and treating physicians was conducted in seven countries: Indonesia, Malaysia, Philippines, Thailand, Vietnam (patient survey only), Saudi Arabia, and the United Arab Emirates. Assessment was carried out through an online/face-to-face questionnaire, where patients' viewpoints were focused on their attitudes and beliefs about asthma and treatment adherence, whereas physicians' viewpoints were gathered on their attitudes and beliefs about asthma management, knowledge of and adherence to asthma treatment guidelines, and asthma treatment regimens.

resultsOverall, 1400 patients (mean age, 34 years) and 599 physicians (mean age, 43 years) were included in the survey. Physicians similarly prioritised symptom control (39%) and exacerbation reduction (40%) in moderate asthma, whereas patients prioritised symptom control (41%) over exacerbation reduction (22%). Although both groups (physicians, 86%; patients, 84%) perceived asthma as well-controlled, poor management was evident based on Asthma Control Test (ACT) scores (mean, 15.7; standard deviation, 4.14; 82% had an ACT score < 20) and high symptom burden (39% reported nighttime awakenings or early mornings ≥ 2 nights/week). Most patients (76%) with moderate asthma were prescribed regular dosing, with the most common treatment being inhaled corticosteroid (ICS)/long-acting β

conclusionsDespite high symptom burden, patients overestimated their level of asthma control. Physicians prioritised controlling symptoms and reducing exacerbations as treatment goals for moderate asthma, often prescribing regular dosing with ICS/LABA with as-needed inhaled SABA.

Indexed as

Anti-Asthmatic AgentsAsthmaAdministration, InhalationAdultAttitude of Health PersonnelCost of IllnessCross-Sectional StudiesDrug MonitoringFemaleHealth Knowledge, Attitudes, PracticeHumansIndonesiaMalaysiaMaleMiddle AgedNebulizers and VaporizersAnti-Asthmatic AgentsAsthmaAsthma controlAsthma exacerbationAsthma regimenGuideline adherencePatient viewpointsPhysician perspectives

Identifiers

PMID38874879
PMCPMC11263244

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.