Evidence map›Paper›PMID 38874770›Full record

ArticleMolecular biology reports2024

Genome and transcriptome exploration reveals receptor-like kinases as potential resistance gene analogs against bacterial blight in pomegranate.

Dattatraya Hegde Radhika, M Nandan, Raghavendra Gunnaiah, Pushpa Doddaraju, Pavan Dumble, Girigowda Manjunatha, Nripendra Vikram Singh

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Article in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Dattatraya Hegde Radhika *Dept. of Biotechnology and Crop Improvement, University of Horticultural Sciences, Bagalkot, 587104, India.ORCID https://orcid.org/0000-0002-9900-4620
M Nandan *Dept. of Biotechnology and Crop Improvement, University of Horticultural Sciences, Bagalkot, 587104, India.
Raghavendra Gunnaiah *Dept. of Biotechnology and Crop Improvement, University of Horticultural Sciences, Bagalkot, 587104, India. raghavendra.gunnaiah@uhsbagalkot.edu.in.ORCID https://orcid.org/0000-0001-8479-3164
Pushpa DoddarajuBiocontrol Laboratory, Directorate of Research, University of Horticultural Sciences, Bagalkot, 587104, India.
Pavan DumbleBiocontrol Laboratory, Directorate of Research, University of Horticultural Sciences, Bagalkot, 587104, India.
Girigowda ManjunathaBiocontrol Laboratory, Directorate of Research, University of Horticultural Sciences, Bagalkot, 587104, India.
Nripendra Vikram SinghNational Research Centre on Pomegranate, Solapur, 413255, India.ORCID https://orcid.org/0000-0003-1760-8592

Funding

Department of Science and Technology, Science and Engineering Research Board, Government of India ECR/2017/000914
6 · The paper itself

Abstract

backgroundPomegranate (Punica granatum L.) is a tropical fruit crop of pharma-nutritional importance. However, it faces farming challenges due to pests and diseases, particularly bacterial blight and wilt. Developing resistant cultivars is crucial for sustainable pomegranate cultivation, and understanding resistance's genetic basis is essential. METHODS AND

resultsWe used an extensive resistance gene analogues (RGA) prediction tool to identify 958 RGAs, classified into Nucleotide Binding Site-leucine-rich repeat (NBS-LRR) proteins, receptor-like kinases (RLKs), receptor-like proteins (RLPs), Transmembrane coiled-coil (TM-CC), and nine non-canonical RGAs. RGAs were distributed across all eight chromosomes, with chromosome 02 containing the most RGAs (161), and chromosome 08 having the highest density (4.42 RGA/Mb). NBS-LRR genes were predominantly present on chromosomes 08 and 02, whereas RLKs and RLPs were primarily located on chromosomes 04 and 07. Gene ontology analysis revealed that 475 RGAs were associated with defence against various biotic stresses. Using RNAseq, we identified 120 differentially expressed RGAs, with RLKs (74) being prominent among the differentially expressed genes.

conclusionThe discovery of these RGAs is a significant step towards breeding pomegranates for pest and disease resistance. The differentially expressed RLKs hold promise for developing resistant cultivars against bacterial blight, thereby contributing to the sustainability of pomegranate cultivation.

Indexed as

Disease ResistancePlant DiseasesPlant ProteinsPomegranateTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantGenome, PlantXanthomonasPlant ProteinsBacterial blightGenome-wide miningNucleotide binding site-leucine-rich repeatPomegranateReceptor-like kinasesReceptor-like proteinsResistance gene analogues

Identifiers

PMID38874770

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