Evidence map›Paper›PMID 38874677›Full record

ArticleNeuroscience bulletin2024

Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Preeclampsia-Induced Apoptosis of Placental Trophoblastic Cells Via Inhibiting the Mitochondrial Unfolded Protein Response.

Jing Zhao, Yanan Yang, Jiayi Qin, Siyu Tao, Chunmei Jiang, Huixuan Huang, Qiunan Wan, Yuqi Chen, Shouzhu Xu, Haifa Qiao

Abstract read
In one paragraph

Article in Neuroscience bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. taVNS alleviates preeclampsia-induced vascular endothelial dysfunction via α7nAChR- IP3R1/GRP75/VDAC1 signal pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jing ZhaoCollege of Acupuncture and Tuina, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Yanan YangDepartment of Public Health, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Jiayi QinCollege of Medical Technology, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Siyu TaoCollege of Acupuncture and Tuina, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Chunmei JiangCollege of Medical Technology, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Huixuan HuangCollege of Medical Technology, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Qiunan WanCollege of Acupuncture and Tuina, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Yuqi ChenCollege of Medical Technology, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China.
Shouzhu XuDepartment of Public Health, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China. xsz90026@163.com.
Haifa QiaoCollege of Acupuncture and Tuina, Shaanxi University of Chinese Medicine, Xixian New Area, Xianyang, 712046, China. 1511006@sntcm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia is a serious obstetric complication. Currently, there is a lack of effective preventive approaches for this disease. Recent studies have identified transcutaneous auricular vagus nerve stimulation (taVNS) as a potential novel non-pharmaceutical therapeutic modality for preeclampsia. In this study, we investigated whether taVNS inhibits apoptosis of placental trophoblastic cells through ROS-induced UPR

Indexed as

ApoptosisMitochondriaPre-EclampsiaTrophoblastsUnfolded Protein ResponseVagus Nerve StimulationAcetylcholineAnimalsFemaleHumansPlacentaPregnancyReactive Oxygen SpeciesTranscutaneous Electric Nerve StimulationAcetylcholineReactive Oxygen SpeciesAcetylcholineMitochondrial unfolded protein responsePlacental trophoblastic cellsPreeclampsiaReactive oxygen speciesTranscutaneous auricular vagus nerve stimulation

Identifiers

PMID38874677
PMCPMC11422338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.