Evidence map›Paper›PMID 38874616›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

Longitudinal decline in peak V̇o

Majd AlGhatrif, Christopher H Morrell, Jerome L Fleg, Paul D Chantler, Samer S Najjar, Lewis C Becker, Luigi Ferrucci, Gary Gerstenblith, Edward G Lakatta

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Majd AlGhatrifLaboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-7642-2643
Christopher H MorrellLaboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0001-5080-7142
Jerome L FlegDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States.
Paul D ChantlerDepartment of Exercise Physiology, West Virginia University, Morgantown, West Virginia, United States.ORCID 0000-0001-6960-9728
Samer S NajjarDepartment of Cardiology, MedStar Heart and Vascular Institute, MedStar Health, Baltimore, Maryland, United States.ORCID 0000-0002-9149-416X
Lewis C BeckerDivision of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, United States.
Luigi FerrucciLaboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-6273-1613
Gary GerstenblithDivision of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, United States.
Edward G LakattaLaboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-4772-0035

Funding

Age Associated Changes In Structural And Functional Cardio-Vascular PropertiesZIAAG000856 · NIA · NATIONAL INSTITUTE ON AGING · PI LAKATTA, EDWARD · 2009 to 2025
$3.4M
Effects Of Age And Conditioning Status On Rest And Exercise Cardiac PerformanceZIAAG000802 · NIA · NATIONAL INSTITUTE ON AGING · PI LAKATTA, EDWARD · 2009 to 2024
$1.1M
HHS | NIH | National Institute on Aging (NIA) Intramural Research Program
6 · The paper itself

Abstract

Aging is associated with a significant decline in aerobic capacity assessed by maximal exercise oxygen consumption (V̇o

Indexed as

AgingCardiac OutputOxygen ConsumptionAdultAgedAged, 80 and overAge FactorsBaltimoreExercise TestExercise ToleranceFemaleHumansLongitudinal StudiesMaleMiddle AgedYoung Adultaerobic capacityagingarteriovenous oxygen differencecardiac outputpeak oxygen consumption

Identifiers

PMID38874616
PMCPMC11442097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.