Article in Radiology. Imaging cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05159323 (Quantitative Parameters of Diffusion Spectrum Imaging), which is not on this map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Xiang Zhang *From the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0002-1128-0242
Ya Qiu *From the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0001-5421-2963
Wei JiangFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0002-6150-0530
Zehong YangFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0001-7562-3710
Mengzhu WangFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0001-5674-4162
Qin LiFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0009-0000-6489-6166
Yeqing LiuFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0009-0009-4466-585X
Xu YanFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0002-9380-2701
Guang YangFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0001-8942-427X
Jun ShenFrom the Department of Radiology (X.Z., Y.Q., W.J., Z.Y., J.S.), Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center (X.Z., Y.Q., W.J., Z.Y., Q.L., Y.L., J.S.), and Department of Pathology (Q.L., Y.L.), Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, People's Republic of China; Department of Radiology, the First People's Hospital of Kashi Prefecture, Kashi, People's Republic of China (Y.Q.); Department of MR Scientific Marketing, Siemens Healthineers, Guangzhou, People's Republic of China (M.W., X.Y.); and Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, People's Republic of China (G.Y.).ORCID 0000-0001-7746-5285
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Purpose To determine whether metrics from mean apparent propagator (MAP) MRI perform better than apparent diffusion coefficient (ADC) value in assessing the tumor-stroma ratio (TSR) status in breast carcinoma. Materials and Methods From August 2021 to October 2022, 271 participants were prospectively enrolled (ClinicalTrials.gov identifier: NCT05159323) and underwent breast diffusion spectral imaging and diffusion-weighted imaging. MAP MRI metrics and ADC were derived from the diffusion MRI data. All participants were divided into high-TSR (stromal component < 50%) and low-TSR (stromal component ≥ 50%) groups based on pathologic examination. Clinicopathologic characteristics were collected, and MRI findings were assessed. Logistic regression was used to determine the independent variables for distinguishing TSR status. The area under the receiver operating characteristic curve (AUC) and sensitivity, specificity, and accuracy were compared between the MAP MRI metrics, either alone or combined with clinicopathologic characteristics, and ADC, using the DeLong and McNemar test. Results A total of 181 female participants (mean age, 49 years ± 10 [SD]) were included. All diffusion MRI metrics differed between the high-TSR and low-TSR groups (
Indexed as
Breast NeoplasmsCarcinoma, Ductal, BreastDiffusion Magnetic Resonance ImagingAdultAgedBreastFemaleHumansMagnetic Resonance ImagingMiddle AgedProspective StudiesSensitivity and SpecificityBreastMR Diffusion-weighted ImagingMR ImagingOncology
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Mean Apparent Propagator MRI: Quantitative Assessment of Tumor-Stroma Ratio in Invasive Ductal Breast Carcinoma. · full record | OpenQuestion