Evidence map›Paper›PMID 38874412›Full record

ArticlemBio2024

Iron limitation induces motility in uropathogenic

A E Frick-Cheng, A E Shea, J R Roberts, S N Smith, M D Ohi, H L T Mobley

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Functional characterization of iucC and iucD in iron acquisition and virulence of Cronobacter sakazakii.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

A E Frick-Cheng *Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-7202-4701
A E Shea *Department of Microbiology and Immunology, University of South Alabama Medical School, Mobile, Alabama, USA.ORCID 0000-0003-1329-3888
J R RobertsLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-9976-5828
S N SmithDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
M D OhiLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
H L T MobleyDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-9195-7665

Funding

Reciprocal Control of Motility and Adherence in UTIR01AI059722 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PEARSON, MELANIE M. · 2005 to 2024
$7.4M
E. coli virulence gene expression during clinical UTIs in womenR01AI165582 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARK T. ANDERSON, MELANIE M. PEARSON · 2022 to 2026
$3.5M
Characterization of pathogen nutrient acquisition and transport systems required during UTIF32AI147527 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHEA, ALLYSON E · 2019 to 2022
$198k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI059722, F32AI147527HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI165582National Science Foundation (NSF) DGE1841052NIAID NIH HHS F32 AI147527NIAID NIH HHS R01 AI059722NIAID NIH HHS R01 AI165582
6 · The paper itself

Abstract

More than half of women will experience a urinary tract infection (UTI) with most cases caused by uropathogenic IMPORTANCE: Urinary tract infections (UTIs) are ubiquitous and responsible for over five billion dollars in associated health care costs annually. Both iron acquisition and motility are highly studied virulence factors associated with uropathogenic

Indexed as

Escherichia coli InfectionsEscherichia coli ProteinsGene Expression Regulation, BacterialUrinary Tract InfectionsUropathogenic Escherichia coliAnimalsDisease Models, AnimalFemaleFlagellaFlagellinIronLocomotionMiceVirulenceEscherichia coli ProteinsFlagellinFliC protein, E coliIronflagellar gene regulationflagellar motilityiron regulationpathogenesisurinary tract infection

Identifiers

PMID38874412
PMCPMC11253704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.