Evidence map›Paper›PMID 38874341›Full record

ArticleJournal of bacteriology2024

ComI inhibits transformation in

Dominique R Smith, Daniel B Kearns, Briana M Burton

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dominique R SmithDepartment of Bacteriology, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0009-0008-3382-2891
Daniel B KearnsDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0002-3460-8378
Briana M BurtonDepartment of Bacteriology, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0002-6444-8213

Funding

Swarming motility and the regulation of flagellar biosynthesis in Bacillus subtilisR35GM131783 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Daniel B Kearns · 2019 to 2026
$3.9M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM131783NIGMS NIH HHS R35 GM131783U.S. Department of Agriculture (USDA) 7000273
6 · The paper itself

Abstract

Many bacteria build elaborate molecular machines to import DNA via natural competence, yet this activity is often not identified until strains have been handled and domesticated in laboratory settings. For example, one of the best studied Gram-positive model organisms, IMPORTANCE: Natural transformation mechanisms have been studied across several bacterial systems, but few examples of inhibition exist. This work investigates the mechanism of action of a plasmid-encoded transmembrane inhibitor of natural transformation. The data reveal that the peptide can cause cell permeabilization. Permeabilization is synergistic with entry of

Indexed as

Bacillus subtilisBacterial ProteinsGene Expression Regulation, BacterialPlasmidsTransformation, BacterialDNA Transformation CompetenceBacterial ProteinsB. subtiliscompetencenatural transformation

Identifiers

PMID38874341
PMCPMC11270867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.