Evidence map›Paper›PMID 38873798›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2024

The impact of living conditions and health interventions on tuberculosis, Denmark, 1876 to 2022.

Anne Christine Nordholm, Anja Joergensen, Louise Hedevang Holm, Aase Bengaard Andersen, Anders Koch, Peter Henrik Andersen, Troels Lillebaek

Abstract readHistorical Article
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne Christine NordholmThese authors contributed equally to the work and share first authorship.
Anja JoergensenThese authors contributed equally to the work and share first authorship.
Louise Hedevang HolmDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Aase Bengaard AndersenDepartment of Infectious Diseases, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark.
Anders KochDepartment of Infectious Diseases, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark.
Peter Henrik AndersenThese authors contributed equally to the work and share last authorship.
Troels LillebaekThese authors contributed equally to the work and share last authorship.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDenmark possesses an exceptional historical data collection on tuberculosis (TB) from 1876 to the present, providing a unique opportunity to assess TB epidemiology over 147 years in Denmark.AimOur aim was to describe the TB disease burden in Denmark in relation to historical events, living conditions and health interventions during the past 147 years.MethodsWe performed a nationwide register-based ecological study including all persons with TB in Denmark from 1876 through 2022, correlating the TB incidence to social, economic and health indicators.ResultsIn Denmark, the overall TB incidence and mortality declined markedly over the past 147 years, only marginally influenced by specific TB interventions such as sanatoria, Bacillus Calmette-Guèrin (BCG) vaccination, mass screenings and antibiotics. Parallel to this decline, the country experienced improved living conditions, as illustrated by decreased infant mortality and increased life expectancy and wealth. In 1978, Denmark became a low-incidence country for TB with risk groups predominantly affected, and with a continuous change in demographics towards fewer Danish-born cases and relatively more migrant cases.ConclusionsThe decline over time in TB incidence and mortality in Denmark preceded specific TB interventions and can, first of all, be attributed to improved living conditions. TB has now become a rare disease in Denmark, predominantly occurring in particular risk groups. Future elimination of TB will require a combination of specific health interventions in these risk groups combined with a continued focus on improving socioeconomic status and living conditions.

Indexed as

RegistriesTuberculosisAdolescentAdultAgedBCG VaccineChildChild, PreschoolDenmarkFemaleHistory, 19th CenturyHistory, 20th CenturyHistory, 21st CenturyHumansIncidenceInfantBCG VaccineDenmarkdisease surveillanceepidemiologyEpidemiologyinfection controlmorbiditymortalitypublic healthsurveillancetuberculosis

Identifiers

PMID38873798
PMCPMC11177568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.