Evidence map›Paper›PMID 38873787›Full record

ArticleJournal of cosmetic dermatology2024

A bibliometric analysis of alternative drug therapy options in the treatment of androgenetic alopecia.

Aditya K Gupta, Daniel Taylor, Shruthi Polla Ravi, Tong Wang, Mesbah Talukder

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aditya K GuptaMediprobe Research Inc., London, Ontario, Canada.ORCID https://orcid.org/0000-0002-8664-7723
Daniel TaylorMediprobe Research Inc., London, Ontario, Canada.ORCID https://orcid.org/0009-0001-7721-2031
Shruthi Polla RaviMediprobe Research Inc., London, Ontario, Canada.ORCID https://orcid.org/0000-0001-7161-0322
Tong WangMediprobe Research Inc., London, Ontario, Canada.ORCID https://orcid.org/0000-0001-9359-9750
Mesbah TalukderSchool of Pharmacy, BRAC University, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0003-0691-640X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral finasteride and topical minoxidil formulations are the only FDA-approved drug therapies for androgenetic alopecia (AGA). Research into dutasteride, topical finasteride, and nontopical minoxidil (low-dose oral and sublingual) formulations in the treatment of AGA has spiked within recent years. Early findings show that these alternative drug therapies may have similar to improved efficacy and safety profiles relative to the conventional treatment options.

aimsConducting a bibliometric analysis, compare trends in publications on these alternative drug therapies, identify key contributors, evaluate major findings from top-cited articles, and elucidate gaps in evidence.

methodsA search was conducted on the Web of Science database for publications on the use of alternative drug therapies in the treatment of AGA. A total of 95 publications, published between January 2003-March 2024, and their citation metadata were included in the analysis.

resultsDutasteride showed the greatest (n = 37) and longest (20+ years) history of publications, as well as the highest cumulative citations (n = 914); however, nontopical minoxidil showed a burst in research activity within the last 5 years (n = 33 publications since 2019). A relatively low number of randomized control trials (n = 3) for nontopical minoxidil suggests a need for higher-quality evidence.

conclusionsOur analysis reveals major trends, contributors, and gaps in evidence for alternative drug therapies for AGA, which can help inform researchers on their future projects in this growing field of study. There is enthusiasm for exploring off-label formulations: nontopical forms of minoxidil (oral and sublingual), topical finasteride, and mesotherapy.

Indexed as

AlopeciaBibliometricsDutasterideFinasterideMinoxidil5-alpha Reductase InhibitorsAdministration, OralAdministration, TopicalHumansRandomized Controlled Trials as TopicTreatment Outcome5-alpha Reductase InhibitorsDutasterideFinasterideMinoxidilandrogenetic alopeciabibliometric analysislow‐dose oral minoxidilsublingual minoxidiltopical finasteride

Identifiers

PMID38873787
PMCPMC13648914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.