Evidence map›Paper›PMID 38873592›Full record

ArticleNature reviews. Methods primers2023

Sulfur fluoride exchange.

Joshua A Homer, Long Xu, Namitharan Kayambu, Qinheng Zheng, Eun Joung Choi, Byeong Moon Kim, K Barry Sharpless, Han Zuilhof, Jiajia Dong, John E Moses

Abstract read
In one paragraph

Article in Nature reviews. Methods primers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. SOChemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Design, Synthesis and Anticancer Evaluation of Novel SOMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Aryl Sulfamoyl [Journal of medicinal chemistry · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Polysulfamates as "Macroisosteres" of Polyurethanes with Improved Degradability.Angewandte Chemie (International ed. in English) · 2025
    Article
  15. Article
  16. Multimodal S(VI) Exchange Click Reactions Derived from SFThe Journal of organic chemistry · 2025
    Article
  17. Article
  18. Diversity Oriented Clicking for Modular Synthesis.Nature reviews. Methods primers · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joshua A HomerCancer Center, Cold Spring Harbor Laboratory, 1 Bungtown Road, NY 11724, USA.
Long XuInstitute of Translational Medicine, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
Namitharan KayambuLaboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Qinheng ZhengDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
Eun Joung ChoiDepartment of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, South Korea.
Byeong Moon KimDepartment of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, South Korea.
K Barry SharplessDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
Han ZuilhofLaboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Jiajia DongInstitute of Translational Medicine, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
John E MosesCancer Center, Cold Spring Harbor Laboratory, 1 Bungtown Road, NY 11724, USA.

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI John Edward Moses · 1987 to 2026
$118.9M
Sulfur(VI) Fluoride Exchange (SuFEx): new developments and biological applicationsR01GM117145 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SHARPLESS, KARL BARRY · 2016 to 2023
$3.9M
NCI NIH HHS P30 CA045508NIGMS NIH HHS R01 GM117145
6 · The paper itself

Abstract

Sulfur Fluoride Exchange (SuFEx) is a click reaction par excellence that has revolutionized multiple research fields. In this Primer, we delve into the essential elements of SuFEx operation, catalysis, and SuFExable connective hubs. We also explore the cutting-edge applications of SuFEx in drug development, polymer science, and biochemistry. Additionally, we examine the potential limitations and promising prospects for this versatile click reaction.

Identifiers

PMID38873592
PMCPMC11171465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.