Evidence map›Paper›PMID 38873576›Full record

ArticleClinical kidney journal2024

Association of calciprotein particles with serum phosphorus among patients undergoing conventional and extended-hours haemodialysis.

Nobuhiro Nishibori, Masaki Okazaki, Yutaka Miura, Manabu Hishida, Shimon Kurasawa, Takahiro Imaizumi, Noritoshi Kato, Tomoki Kosugi, Makoto Kuro-O, Hirotake Kasuga and 2 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The formation and function of calciprotein particles.Pflugers Archiv : European journal of physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nobuhiro NishiboriDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0001-8098-1205
Masaki OkazakiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0003-3711-3925
Yutaka MiuraDivision of Anti-Aging Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
Manabu HishidaDepartment of Nephrology, Kaikoukai Josai Hospital, Nagoya, Japan.ORCID https://orcid.org/0000-0002-6068-8228
Shimon KurasawaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0001-6692-2380
Takahiro ImaizumiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0003-3831-7241
Noritoshi KatoDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tomoki KosugiDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0002-6319-5728
Makoto Kuro-ODivision of Anti-Aging Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
Hirotake KasugaDepartment of Nephrology, Nagoya Kyoritsu Hospital, Nagoya, Japan.ORCID https://orcid.org/0000-0001-6319-5728
Fumika KanedaKamome Clinic, Hitachi, Japan.
Shoichi MaruyamaDepartment of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0002-8858-632X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and hypothesis: Extended-hours haemodialysis (HD) is associated with better clinical outcomes than conventional HD. We investigated whether extended-hours HD and conventional HD have varying effects on blood levels of calciprotein particles (CPPs) and phosphorus, which have been identified as major pathogenic molecules for vascular calcification. Methods: Patients who underwent conventional or extended in-centre daytime HD between January and March 2020 were included. Plasma CPP levels, representing only secondary CPPs (CPP-II), were measured in pre-dialysis samples. Linear and non-linear associations between CPPs and serum phosphorus levels were examined across dialysis modalities. Results: A total of 382 participants (185 undergoing extended-hours HD and 197 undergoing conventional HD) were included in the analysis. The median age of participants was 71 years, 65% of the patients were men and the mean phosphorus level was 5.4 mg/dl. Plasma CPP (CPP-II) levels were lower in the extended-hours HD group than in the conventional HD group [40 018 (arbitrary units) AU versus 75 728 AU; Conclusions: The extended-hours HD group had lower CPP levels than the conventional HD group despite no significant differences in serum phosphorus levels, which may contribute to better clinical outcomes in patients on extended-hours HD.

Indexed as

calcificationchronic haemodialysisend-stage kidney diseasemineral bone disordernutrition

Identifiers

PMID38873576
PMCPMC11170037

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.