Evidence map›Paper›PMID 38873548›Full record

ArticleRSC advances2024

Enhanced fluorometric detection of histamine using red emissive amino acid-functionalized bimetallic nanoclusters.

Yahya S Alqahtani, Ashraf M Mahmoud, Al-Montaser Bellah H Ali, Mohamed M El-Wekil

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yahya S AlqahtaniDepartment of Pharmaceutical Chemistry, College of Pharmacy, Najran University Najran 11001 Saudi Arabia mohamed.mohamoud@ymail.com.
Ashraf M MahmoudDepartment of Pharmaceutical Chemistry, College of Pharmacy, Najran University Najran 11001 Saudi Arabia mohamed.mohamoud@ymail.com.
Al-Montaser Bellah H AliDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University Assiut 71516 Egypt mohamed.elwakeel@pharm.aun.edu.eg.
Mohamed M El-WekilDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University Assiut 71516 Egypt mohamed.elwakeel@pharm.aun.edu.eg.ORCID https://orcid.org/0000-0002-1097-1148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysine-capped gold nanoclusters doped with silver (LYS@Ag/Au NCs) have been developed for the sensitive and selective "turn-off" fluorescence detection of histamine. This fluorescent probe demonstrates excellent stability and a high quantum yield of 9.45%. Upon addition of histamine, a positively charged biogenic amine, to the LYS@Ag/Au NCs fluorescent probe, its fluorescence emission is quenched due to electrostatic interaction, aggregation, and hydrogen bond formation. The probe exhibits good sensitivity for the determination of histamine within the range of 0.003-350 μM, with a detection limit of 0.001 μM based on a signal-to-noise ratio of 3. Furthermore, the probe has been applied to detect biogenic amines in complicated matrices, highlighting its potential for practical applications. However, interference from the analogue histidine was observed during analysis, which can be mitigated by using a Supelclean™ LC-SAX solid-phase extraction column for removal.

Identifiers

PMID38873548
PMCPMC11168285

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.