ArticleFood science & nutrition2024
Optimization of an ultrasound-assisted extraction method to obtain gallic acid-rich extracts from mango seed kernels.
Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Valorization of Mango By-Products: Bioactive Potential of Peel and Seeds and Their In Vitro Bioavailability.Molecules (Basel, Switzerland) · 2026Article
- Dietary Phytochemicals in Health and Disease: Mechanisms, Clinical Evidence, and Applications-A Comprehensive Review.Food science & nutrition · 2025Review
- Dietary polyphenols and human health: sources, biological activities, nutritional and immunological aspects, and bioavailability- a comprehensive review.Frontiers in immunology · 2025Review
- Polyphenols: Secondary Metabolites with a Biological Impression.Nutrients · 2024Review
- Ultrasound-assisted extraction of bioactive compounds from longan seeds powder: Kinetic modelling and process optimization.Ultrasonics sonochemistry · 2024Article
- Optimization of an ultrasound-assisted extraction method to obtain gallic acid-rich extracts from mango seed kernels.Food science & nutrition · 2024Article
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7 authors.
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Abstract
Gallic acid is a widely recognized bioactive compound that falls under the category of secondary polyphenolic metabolites and is fairly found in mango fruit waste, specifically in mango seed kernel (MSK). This study aimed to adopt a green extraction approach to extract this valuable compound via ultrasound-assisted extraction (UAE) without using organic solvents but only water to obtain hazard-free extracts, and the cost of extraction can be minimal. pH (2-8), solvent ratio (20-60 mL/g), temperature (30-60°C) and time (30-60 min) of extraction were the independent variables used for extraction optimization. Single-factor experiments to obtain working ranges for selected extraction variables were carried out. A central composite design using response surface methodology was used to determine the optimum condition to obtain the maximum yield of gallic acid from MSK. The optimized extraction conditions were 3.9 pH, 36.25 mL/g solvent ratio, and 39.4°C of extraction temperature for 21.3 min. As a result, the optimized yield was 5.76 ± 0.41 mg/g, which was comparably equal to and/or better than the other solvent extraction systems. The results showed that gallic acid could efficiently be extracted via UAE under these optimal conditions. It is safer than extraction systems involving hazardous solvents that can be feasibly used for its nutraceutical and therapeutic applications.
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