Evidence map›Paper›PMID 38873328›Full record

ArticleJournal of vascular surgery cases and innovative techniques2024

Acute aortoiliac thrombosis and mitral valve regurgitation as acute onset of eosinophilic granulomatosis with polyangiitis in a 26-year-old patient.

Luca Galassi, Giulia Lerva, Davide Passolunghi, Giovanni Marchetto, Maria Rosa Pozzi, Valerio Stefano Tolva

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Luca GalassiSchool of Vascular and Endovascular Surgery, University of Milan, Milan, Italy.
Giulia LervaSchool of Vascular and Endovascular Surgery, University of Milan, Milan, Italy.
Davide PassolunghiCardiac Surgery Unit, IRCCS San Gerardo Dei Tintori, Monza, Italy.
Giovanni MarchettoCardiac Surgery Unit, IRCCS San Gerardo Dei Tintori, Monza, Italy.
Maria Rosa PozziRheumatology Unit, IRCCS San Gerardo Dei Tintori, Monza, Italy.
Valerio Stefano TolvaVascular and Endovascular Surgery Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a rare case of eosinophilic granulomatosis with polyangiitis (EGPA), involving a 26-year-old woman with a history of asthma and nasal polyps. The patient presented with acute aortoiliac thrombosis and mitral insufficiency, which was successfully treated with thrombolysis, aortic thromboendarterectomy, and valve replacement. Peripheral hypereosinophilia with eosinophilic infiltration of the heart led to the diagnosis of antineutrophilic cytoplasmic antibody-negative EGPA. Treatment with prednisone and mepolizumab was started, resulting in a positive outcome. This case showcases an unusual manifestation of EGPA with large size vessel involvement and requiring surgical and pharmacological treatment. It also highlights the importance of early detection for timely intervention and an improved prognosis.

Indexed as

Acute arterial thrombosisChurg-Strauss syndromeMitral valve regurgitation

Identifiers

PMID38873328
PMCPMC11170480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.