Evidence map›Paper›PMID 38873093›Full record

ArticleFrontiers in neuroanatomy2024

Regional and cellular organization of the autism-associated protein UBE3A/E6AP and its antisense transcript in the brain of the developing rhesus monkey.

Chavely Gonzalez Ramirez, Sarah G Salvador, Ridthi Kartik Rekha Patel, Sarah Clark, Noah W Miller, Lucas M James, Nicholas W Ringelberg, Jeremy M Simon, Jeffrey Bennett, David G Amaral and 2 more

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chavely Gonzalez Ramirez *Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Sarah G Salvador *Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Ridthi Kartik Rekha PatelNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Sarah ClarkNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Noah W MillerNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Lucas M JamesNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Nicholas W RingelbergNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Jeremy M SimonDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Jeffrey BennettDepartment of Psychiatry and Behavioral Sciences, MIND Institute, Davis, CA, United States.
David G AmaralDepartment of Psychiatry and Behavioral Sciences, MIND Institute, Davis, CA, United States.
Alain C BuretteNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Benjamin D PhilpotNeuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
UNC Neuroscience Center Research Cores: MicroscopyP30NS045892 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZYLKA, MARK J. · 2003 to 2022
$11.5M
Preclinical CoreP50HD103573 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GABRIEL S DICHTER · 2020 to 2026
$9.7M
UBE3A gain-of-function and parent-of-origin influence on neurodevelopmental phenotypesR01MH120229 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PHILPOT, BENJAMIN D, ZYLKA, MARK J. · 2019 to 2023
$3.4M
Small Molecule Therapeutic Discovery for Angelman SyndromeR01NS131615 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Jeffrey Aube, BENJAMIN D PHILPOT · 2023 to 2026
$2.3M
TCF4 in Pitt-Hopkins syndromeR01NS114086 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PHILPOT, BENJAMIN D · 2019 to 2023
$1.7M
Investigating UBE3A as a driver gene in Duplication 15q syndromeR01NS129914 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT · 2023 to 2026
$1.6M
Super Resolution STED Microscopy at UNCS10OD030300 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GUPTON, STEPHANIE · 2022 to 2022
$600k
NICHD NIH HHS P50 HD103573NIH HHS P51 OD011107NIH HHS S10 OD030300NIMH NIH HHS R01 MH120229NINDS NIH HHS P30 NS045892NINDS NIH HHS R01 NS114086NINDS NIH HHS R01 NS129914NINDS NIH HHS R01 NS131615
6 · The paper itself

Abstract

Angelman syndrome (AS) is a neurogenetic disorder caused by mutations or deletions in the maternally-inherited

Indexed as

Angelman syndromeDup15q syndromeE6-APhippocampusrhesus macaqueUBE3A-ATS

Identifiers

PMID38873093
PMCPMC11169893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.