Evidence map›Paper›PMID 38872698›Full record

ArticleCureus2024

Addressing the Global Threat of Multidrug-Resistant Infections: The Role of Ceftazidime-Avibactam Revisited.

Sreejith Raveendran, Deepashree R, Sujatha Shimoga Ravi Kumar, Krishna Karthik

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sreejith RaveendranMicrobiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, IND.
Deepashree RClinical Microbiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, IND.
Sujatha Shimoga Ravi KumarMedical Microbiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, IND.
Krishna KarthikMicrobiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysore, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective Bloodstream infections (BSIs) due to multidrug-resistant Gram-negative bacteria (MDR-GNB) pose a significant global health threat amid rising antimicrobial resistance (AMR). This study aimed to investigate the efficacy of ceftazidime-avibactam (CZA) as a therapeutic option for these infections, addressing the urgent need for novel treatments. Materials and methods This study was conducted over one year in the Department of Microbiology, JSS Medical College and Hospital, Mysuru, India, and employed a laboratory-based prospective design. From a total of 376 positive blood cultures, 147 multidrug-resistant (MDR) organisms were identified, and 100 were randomly selected for final analysis. Susceptibility testing via disk diffusion and minimum inhibitory concentration (MIC) determination was performed to evaluate CZA efficacy. Results

Indexed as

antimicrobial resistanceceftazidime-avibactamgram negative bacteremiagram negative rodsmulti-drug resistant organism (mdro)

Identifiers

PMID38872698
PMCPMC11169094

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.