Evidence map›Paper›PMID 38872313›Full record

ArticleFoot & ankle international2024

Characteristics of Patients Not Receiving Chemical Thromboprophylaxis Following Foot and Ankle Surgery: Data From the Multicenter, Prospective UK Foot and Ankle Thrombo-Embolism Audit (UK-FATE).

Karan Malhotra, Linzy Houchen-Wolloff, Lyndon Mason, Jitendra Mangwani, UK-FATE Collaborative

Abstract readMulticenter Study
In one paragraph

Article in Foot & ankle international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Karan MalhotraFoot & Ankle Unit, Royal National Orthopaedic Hospital, Stanmore, United Kingdom.ORCID 0000-0001-7589-5310
Linzy Houchen-WolloffUniversity Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Lyndon MasonLiverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.ORCID 0000-0002-0371-3183
Jitendra MangwaniAcademic Team of Musculoskeletal Surgery, University Hospitals of Leicester, Leicester, United Kingdom.
UK-FATE Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the rate of venous thromboembolism (VTE) after foot and ankle surgery is low, multiple factors influence risk for individual patients. Furthermore, there are no clear guidelines on which patients may benefit from chemical thromboprophylaxis. Our aim was to assess patients not treated with chemical thromboprophylaxis after foot and ankle surgery, and to report on their specific patient and surgical risk factors for VTE.

methodsThis was a multicenter, prospective, national audit of patients undergoing foot and ankle surgery (including Achilles tendon ruptures) from 68 participating UK centers. The study was conducted between June 1, 2022, and November 30, 2022, with a further 3-month follow-up. Following data cleansing, 3309 patients were included who did not receive postoperative thromboprophylaxis.

resultsMost patients were elective cases (2589 patients, 78.24%) with ASA grade I or II (2679 patients, 80.96%), fully weightbearing postoperatively (2752 patients, 83.17%), and either without ankle splintage, or splinted in a plantigrade boot (2797 patients, 84.53%). The VTE rate was 0.30% overall (11 cases), with no VTE-related mortality. No single demographic, surgical, or postoperative factor was associated with reduced risk of VTE. However, patients who had elective or trauma surgery not involving the ankle, who were ASA grade I or II and who were weightbearing immediately postoperatively (without splinting or in a plantigrade boot) had a VTE rate of 0.05% (1 of 1819 patients), compared with 0.67% (10 of 1490 patients,

conclusionPatients not receiving chemical thromboprophylaxis had a low incidence of symptomatic VTE, although they do represent a curated group considered lower risk. Within this group we describe characteristics associated with a substantially lower risk of VTE. All patients should be assessed on an individual basis, and further work is required to substantiate our findings.

Indexed as

Postoperative ComplicationsVenous ThromboembolismAdultAgedAnkleAnticoagulantsFemaleFootHumansMaleMedical AuditMiddle AgedOrthopedic ProceduresProspective StudiesRisk FactorsUnited KingdomAnticoagulantsfoot; anklesurgerythromboprophylaxisUK-FATEvenous thromboembolism

Identifiers

PMID38872313
PMCPMC11408974

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