Evidence map›Paper›PMID 38872263›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Self-Assembled Aza-Boron-Dipyrromethene-Based H

Jiajia Zhao, Erbao Bian, Renwu Zhang, Tao Xu, Yang Nie, Linqi Wang, Gui Jin, Han Xie, Huijing Xiang, Yu Chen and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  10. Review
  11. Self-Assembled Aza-Boron-Dipyrromethene-Based HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiajia ZhaoDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Erbao BianDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Renwu ZhangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Tao XuDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, 200003, P. R. China.
Yang NieDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Linqi WangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Gui JinDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Han XieDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.
Huijing XiangSchool of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China.
Yu ChenSchool of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China.ORCID 0000-0002-8206-3325
Dejun WuDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, P. R. China.

Funding

Basic Research Program of Shanghai Municipal Government 21JC1406002National Natural Science Foundation of China 32171391National Natural Science Foundation of China 81972348National Natural Science Foundation of China T2322018Shanghai Rising-Star Program 22QA1403600Shanghai Science and Technology Program 21010500100
6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) is the most aggressive and lethal subtype of gliomas of the central nervous system. The efficacy of sonodynamic therapy (SDT) against GBM is significantly reduced by the expression of apoptosis-inhibitory proteins in GBM cells. In this study, an intelligent nanoplatform (denoted as Aza-BD@PC NPs) based on the aza-boron-dipyrromethene dye and phenyl chlorothionocarbonate-modified DSPE-PEG molecules is developed for synergistic ferroptosis-enabled gas therapy (GT) and SDT of GBM. Once internalized by GBM cells, Aza-BD@PC NPs showed effective cysteine (Cys) consumption and Cys-triggered hydrogen sulfide (H

Indexed as

FerroptosisGlioblastomaHydrogen SulfideProdrugsAnimalsCell Line, TumorDisease Models, AnimalHumansMiceUltrasonic TherapyHydrogen SulfideProdrugsferroptosisgas therapyglioma treatmentnanomedicinesonodynamic therapy

Identifiers

PMID38872263
PMCPMC11321684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.