Evidence map›Paper›PMID 38872099›Full record

ArticleJournal of neurodevelopmental disorders2024

Developmental associations between cognition and adaptive behavior in intellectual and developmental disability.

Andrew Dakopolos, Emma Condy, Elizabeth Smith, Danielle Harvey, Aaron J Kaat, Jeanine Coleman, Karen Riley, Elizabeth Berry-Kravis, David Hessl

Abstract read
In one paragraph

Article in Journal of neurodevelopmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Cognitive Profile of Autism and Intellectual Disorder in Wechsler's Scales: Meta-Analysis.European journal of investigation in health, psychology and education · 2026
    Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Andrew DakopolosUC Davis MIND Institute and Department of Psychiatry and Behavioral Sciences, 2825 50th Street, Sacramento, CA, 95817, USA.
Emma CondyHofstra University, 1000 Hempstead Tpke, Hempstead, NY, 11549, USA.
Elizabeth SmithCincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA.
Danielle HarveyDivision of Biostatistics, Department of Public Health Sciences, UC Davis, Medical Sciences 1C, One Shields Avenue, Davis, CA, 95616, USA.
Aaron J KaatFeinberg School of Medicine, Northwestern University, 625 N. Michigan Ave Suite 2700, Chicago, IL, 60611, USA.
Jeanine ColemanRegis University, 3333 Regis Boulevard, Denver, CO, 80221, USA.
Karen RileySlippery Rock University of Pennsylvania, 104 Maltby Ave, Slippery Rock, PA, 16057, USA.
Elizabeth Berry-KravisRush University Medical Center, 600 Paulina St., Chicago, IL, 60012, USA.
David HesslUC Davis MIND Institute and Department of Psychiatry and Behavioral Sciences, 2825 50th Street, Sacramento, CA, 95817, USA. drhessl@ucdavis.edu.ORCID 0000-0002-3460-9805

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
A Cognitive Test Battery for Intellectual DisabilitiesR01HD076189 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVID R HESSL · 2014 to 2026
$8.6M
POPULATION-BASED BIRTH DEFECTS SURVEILLANCE AND UTILAZATION OF SURVEILLANCE DATA U50DD000596 · DD · COLORADO STATE DEPT/PUB HLTH & ENVIRONMT · PI RUTTENBER, MARGARET · 2010 to 2015
$1.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development HD076189Eunice Kennedy Shriver National Institute of Child Health and Human Development P50HD103526NCBDD CDC HHS U50 DD000596NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD076189Office of Human Development Services 90DD0596
6 · The paper itself

Abstract

backgroundIntellectual and developmental disabilities (IDDs) are associated with both cognitive challenges and difficulties in conceptual, social, and practical areas of living, commonly referred to as adaptive behavior (DSM-5). Although cross-sectional associations between intelligence or cognition and adaptive behavior have been reported in IDD populations, no study to date has examined whether developmental changes in cognition contribute to or track with changes in adaptive behavior. The present study sought to examine associations of longitudinal developmental change in domains of cognition (NIH Toolbox Cognition Battery, NIHTB-CB) and adaptive behavior domains (Vineland Adaptive Behavior Scales-3; VABS-3) including Socialization, Communication, and Daily Living Skills (DLS) over a two year period in a large sample of children, adolescents and young adults with IDD.

methodsThree groups were recruited, including those with fragile X syndrome, Down syndrome, and other/idiopathic intellectual disability. Eligible participants (n = 263) included those who were between 6 and 26 years (m

resultsOver a two year period, change in cognition (both Crystallized and Total Composites) was significantly and positively associated with change in daily living skills. Also, baseline cognition level predicted growth in adaptive behavior, however baseline adaptive behavior did not predict growth in cognition in any model.

conclusionsThe present study demonstrated that developmental changes in cognition and adaptive behavior are associated in children and young adults with IDD, indicating the potential for cross-domain effects of intervention. Notably, improvements in DLS emerged as a primary area of adaptive behavior that positively related to improvements in cognition. This work provides evidence for the clinical, "real life" meaningfulness of changes in cognition detected by the NIHTB-CB in IDD, and provides empirical support for the NIHTB-CB as a fit-for-purpose performance-based outcome measure for this population.

Indexed as

Adaptation, PsychologicalCognitionDevelopmental DisabilitiesIntellectual DisabilityActivities of Daily LivingAdolescentAdultChildDown SyndromeFemaleFragile X SyndromeHumansLongitudinal StudiesMaleSocializationYoung AdultAdaptive behaviorCognitionDown syndromeFragile X syndromeIntellectual and developmental disabilityLatent changeLongitudinal studiesNIH ToolboxStructural equation modeling

Identifiers

PMID38872099
PMCPMC11177479

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.