Evidence map›Paper›PMID 38872077›Full record

ArticleBMC neurology2024

Process approach as a cognitive biomarker related to gray matter volume in mild cognitive impairment and Alzheimer's disease.

Wenhao Zhu, Xia Zhou, Mengmeng Ren, Wenwen Yin, Yating Tang, Jiabin Yin, Yue Sun, Xiaoqun Zhu, Zhongwu Sun

Abstract read
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In one paragraph

Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenhao Zhu *Department of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Xia Zhou *Department of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Mengmeng RenDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Wenwen YinDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Yating TangDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Jiabin YinDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Yue SunDepartment of Neurology, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaoqun ZhuDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China.
Zhongwu SunDepartment of Neurology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, 230022, China. sunzhwu@126.com.

Funding

Anhui Provincial Key Research and Development Plan 202104j07020031
6 · The paper itself

Abstract

backgroundProcess approach is valuable for memory assessment in Alzheimer's disease (AD) and mild cognitive impairment (MCI), yet its underlying mechanisms remain elusive. This study aims to synergize the process approach with brain structure analysis to explore both the discriminative capacity and potential mechanisms underlying the process approach.

methods37 subjects of MCI, 35 subjects of AD and 38 subjects of healthy control (HC) were included. The process approach in Auditory Verbal Learning Test (AVLT), including discriminability (A'), response bias (B"

resultsROC analysis showed the value of A', B"

conclusionThis study indicated that the process approach is a promising cognitive biomarker to detect MCI and AD.

Indexed as

Alzheimer DiseaseBiomarkersCognitive DysfunctionGray MatterMagnetic Resonance ImagingAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeuropsychological TestsBiomarkersAlzheimer’s diseaseGray matter volumeMild cognitive impairmentNeuropsychological assessmentProcess approach

Identifiers

PMID38872077
PMCPMC11170873

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.