Evidence map›Paper›PMID 38872058›Full record

ArticleDysphagia2025

Can Voice Parameters Provide Cutoff Values to Predict Dysphagia in Individuals with Multiple Sclerosis?

Merve Sapmaz Atalar, Gençer Genç, Elif Ezgi Işık, Mehmet Emrah Cangi, Beyza Pehlivan, Serpil Bulut

Abstract read
In one paragraph

Article in Dysphagia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Merve Sapmaz AtalarDepartment of Speech and Language Therapy, Hamidiye Faculty of Health Science, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0003-2556-1026
Gençer GençDepartment of Neurology, Şişli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0002-8094-3062
Elif Ezgi IşıkDepartment of Speech and Language Therapy, Hamidiye Faculty of Health Science, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0001-7722-414X
Mehmet Emrah CangiDepartment of Speech and Language Therapy, Hamidiye Faculty of Health Science, University of Health Sciences, İstanbul, Türkiye. mehmetemrah.cangi@sbu.edu.tr.ORCID 0000-0001-8149-3254
Beyza PehlivanDepartment of Speech and Language Therapy, Hamidiye Faculty of Health Science, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0001-6880-8557
Serpil BulutDepartment of Neurology, Şişli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, İstanbul, Türkiye.ORCID 0000-0003-0395-3299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In dysphagia assessment, along with well-defined measurements and signs, voice parameters can potentially support clinical decision as a marker, but more evidence is needed. This study aims to determine the voice parameters that can predict the risk of dysphagia and to determine optimal cutoff values in individuals with multiple sclerosis (IwMS). Seventy-six adults participated in the study, including 39 IwMS and 37 healthy individuals (HI). The study used the Dysphagia in Multiple Sclerosis Questionnaire (DYMUS), Gugging Swallowing Screen (GUSS), and Voice Handicap Index (VHI-10) and recorded voice samples using Praat programme. Voice recordings were taken pre- and post-swallowing. The voice parameters analysed are fundamental frequency (F0), standard deviation F0 (SD F0), jitter (local), shimmer (local), and harmonic-to-noise ratio (HNR). Roc analysis was performed to examine the diagnostic accuracy performance of the risk for dysphagia/penetration. The parameters of IwMS pre-swallowing differed significantly from those of HI on the VHI-10, DYMUS, GUSS scores, and jitter (local), shimmer (local), and HNR. IwMS but not HI exhibited significant differences in shimmer (local) and HNR between the pre- and post-swallowing measurements. In IwMS, GUSS revealed significant differences in shimmer (local) pre- and post-swallowing between the groups with and without dysphagia/penetration. In the ROC analysis results, the area under the curve (AUC) for shimmer (local) pre-swallowing was 73.1% (cutoff = 1.69); post-swallowing, it was 78.6% (cutoff = 1.57). In conclusion, IwMS can be associated with differences in shimmer (local) and HNR parameters, low quality of life-related to voice, and dysphagia/penetration risk. The AUC values for shimmer (local) in IwMS pre- and post-swallowing may help to strengthen diagnostic decisions of dysphagia risk.

Indexed as

Deglutition DisordersMultiple SclerosisVoice QualityAdultDeglutitionFemaleHumansMaleMiddle AgedPredictive Value of TestsROC CurveSurveys and QuestionnairesDiagnostic accuracyDysphagiaMultiple sclerosisSwallowingVoice parameters

Identifiers

PMID38872058
PMCPMC11762594

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.