Evidence map›Paper›PMID 38872054›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2024

Combining genome-wide association study and linkage mapping in the genetic dissection of amylose content in maize (Zea mays L.).

Wei Dai, Qinglin Li, Tao Liu, Ping Long, Yao He, Mengxiang Sang, Chaoying Zou, Zhong Chen, Guangsheng Yuan, Langlang Ma and 2 more

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Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Combined linkage mapping and association analysis reveal the genetic control of starch content in maize kernel.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  2. Review
  3. Genetic dissection of oil content in maize kernel using combined genome-wide association analysis and linkage mapping.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  4. Review
  5. Article
  6. Quantitative trait locus analysis of gray leaf spot resistance in the maize IBM Syn10 DH population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei DaiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Qinglin LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Tao LiuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Ping LongState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Yao HeState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Mengxiang SangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Chaoying ZouState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Zhong ChenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Guangsheng YuanState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Langlang MaState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Guangtang PanState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China.
Yaou ShenState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Maize Research Institute, Sichuan Agricultural University, Chengdu, 611130, China. shenyaou@sicau.edu.cn.ORCID http://orcid.org/0000-0001-7603-0108

Funding

Biological Breeding Project of National Key Laboratory SKL-ZD202211National Key Research and Development Program of China 2021YFF1000303National Nature Science Foundation of China 32101777National Nature Science Foundation of China 32372203Sichuan Province Science and Technology Support Program 2021JDTD0004Sichuan Province Science and Technology Support Program 2021YJ0476
6 · The paper itself

Abstract

key messageIntegrated linkage and association analysis revealed genetic basis across multiple environments. The genes Zm00001d003102 and Zm00001d015905 were further verified to influence amylose content using gene-based association study. Maize kernel amylose is an important source of human food and industrial raw material. However, the genetic basis underlying maize amylose content is still obscure. Herein, we used an intermated B73 × Mo17 (IBM) Syn10 doubled haploid population composed of 222 lines and a germplasm set including 305 inbred lines to uncover the genetic control for amylose content under four environments. Linkage mapping detected 16 unique QTL, among which four were individually repeatedly identified across multiple environments. Genome-wide association study revealed 17 significant (P = 2.24E-06) single-nucleotide polymorphisms, of which two (SYN19568 and PZE-105090500) were located in the intervals of the mapped QTL (qAC2 and qAC5-3), respectively. According to the two population co-localized loci, 20 genes were confirmed as the candidate genes for amylose content. Gene-based association analysis indicated that the variants in Zm00001d003102 (Beta-16-galactosyltransferase GALT29A) and Zm00001d015905 (Sugar transporter 4a) affected amylose content across multi-environment. Tissue expression analysis showed that the two genes were specifically highly expressed in the ear and stem, respectively, suggesting that they might participate in sugar transport from source to sink organs. Our study provides valuable genetic information for breeding maize varieties with high amylose.

Indexed as

AmyloseChromosome MappingPolymorphism, Single NucleotideQuantitative Trait LociZea maysGenes, PlantGenetic Association StudiesGenetic LinkageGenome-Wide Association StudyGenotypePhenotypeAmylose

Identifiers

PMID38872054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.