Evidence map›Paper›PMID 38871999›Full record

ArticleNature immunology2024

Eomes expression identifies the early bone marrow precursor to classical NK cells.

Zhitao Liang, Hope D Anderson, Veronica Locher, Crystal O'Leary, Samantha J Riesenfeld, Bana Jabri, Benjamin D McDonald, Albert Bendelac

Abstract read
In one paragraph

Article in Nature immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. CD127International journal of molecular sciences · 2026
    Article
  3. Review
  4. T-bet Fate Mapping Reveals Gestational Stage-Specific Transcriptional Adaptation of Decidual NK Cells.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhitao Liang *Committee on Immunology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-5320-6107
Hope D Anderson *Biophysical Sciences Graduate Program, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-5049-7452
Veronica LocherCommittee on Immunology, University of Chicago, Chicago, IL, USA.
Crystal O'LearyDepartment of Pathology, University of Chicago, Chicago, IL, USA.
Samantha J RiesenfeldCommittee on Immunology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-9144-021X
Bana JabriCommittee on Immunology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7427-4424
Benjamin D McDonaldDepartment of Medicine, University of Chicago, Chicago, IL, USA. benjamin.mcdonald@uchicagomedicine.org.ORCID http://orcid.org/0000-0003-1308-8788
Albert BendelacCommittee on Immunology, University of Chicago, Chicago, IL, USA.

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 1990 to 2025
$29.8M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7M
Research Training in Digestive Health, Diseases, and NutritionT32DK007074 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG · 1986 to 2026
$11.3M
Transcriptional Regulation of Innate-Like T CellsR01AI038339 · NIAID · UNIVERSITY OF CHICAGO · PI ESTERHAZY, DARIA · 1996 to 2025
$7.6M
Transcriptional Regulation of Innate-Like T CellsR37AI038339 · NIAID · UNIVERSITY OF CHICAGO · PI BENDELAC, ALBERT S. · 2017 to 2023
$3.4M
Development of Intestinal Polyreactive IgA B CellsR01AI144094 · NIAID · UNIVERSITY OF CHICAGO · PI BENDELAC, ALBERT S. · 2019 to 2023
$2.5M
Probing short and long term consequences of Small and Large Bowel Microbiota Transplants on Host Physiology: Implications for the development of future live biotherapeuticsR01DK138072 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Kristina Brooke Martinez-Guryn · 2024 to 2026
$2.1M
National Science Foundation (NSF) 2140001NIAID NIH HHS R01 AI038339NIAID NIH HHS R01 AI144094NIAID NIH HHS R37 AI038339NIAID NIH HHS T32 AI007090NIDDK NIH HHS P30 DK042086NIDDK NIH HHS R01 DK138072NIDDK NIH HHS T32 DK007074UChicago | Digestive Diseases Reseach Core Center, University of Chicago (DDRCC, Uchicago) P30-DK42086U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 5R01-AI144094U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) T32 DK007074-47
6 · The paper itself

Abstract

Natural killer (NK) cells traffic through the blood and mount cytolytic and interferon-γ (IFNγ)-focused responses to intracellular pathogens and tumors. Type 1 innate lymphoid cells (ILC1s) also produce type 1 cytokines but reside in tissues and are not cytotoxic. Whether these differences reflect discrete lineages or distinct states of a common cell type is not understood. Using single-cell RNA sequencing and flow cytometry, we focused on populations of TCF7

Indexed as

Killer Cells, NaturalT-Box Domain ProteinsAnimalsBone Marrow CellsCell DifferentiationCell LineageImmunity, InnateMiceMice, Inbred C57BLMice, KnockoutSingle-Cell AnalysisEomes protein, mouseT-Box Domain Proteins

Identifiers

PMID38871999
PMCPMC11409033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.