Evidence map›Paper›PMID 38871930›Full record

ArticleAnnals of hematology2024

Hepatic, gastric and bone marrow AL amyloidosis that began with Budd-Chiari syndrome: a case report.

Valentina Maria Manieri, Massimo Offidani, Debora Capelli, Marco Marzioni, Luca Maroni, Alessandra Filosa, Serena Rupoli, Erika Morsia, Antonella Poloni, Sonia Morè

Abstract readCase Reports
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In one paragraph

Article in Annals of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valentina Maria ManieriClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Massimo OffidaniClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Debora CapelliClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Marco MarzioniClinica di Gastroenterologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Luca MaroniClinica di Gastroenterologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Alessandra FilosaAnatomia Patologica, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Serena RupoliClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Erika MorsiaClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Antonella PoloniClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Sonia MorèClinica di Ematologia, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy. s.more@staff.univpm.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid Light Chain (AL) Amyloidosis is a rare disorder of protein misfolding and metabolism characterized by insoluble fibrils deposition in various tissues and organs, which could quickly progress and become fatal. The most frequently affected organ is heart being its involvement the most adverse prognostic feature. Kidney and liver could be other organ localizations, defining AL Amyloidosis as a multisystem disorder. Being Budd-Chiari syndrome (BCS) an uncommon congestive hepatopathy caused by blockage of hepatic veins in the absence of cardiac disorders, it could be rarely caused by a massive deposition of amyloid proteins into hepatic sinusoidal spaces, giving an uncommon clinical presentation of AL Amyloidosis.

Indexed as

Bone MarrowBudd-Chiari SyndromeImmunoglobulin Light-chain AmyloidosisAmyloidosisHumansLiverLiver DiseasesMiddle AgedAL AmyloidosisBudd-ChiariHepatic amyloidosis

Identifiers

PMID38871930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.