Evidence map›Paper›PMID 38871712›Full record

ArticleNature communications2024

A non-methanogenic archaeon within the order Methanocellales.

Shino Suzuki, Shun'ichi Ishii, Grayson L Chadwick, Yugo Tanaka, Atsushi Kouzuma, Kazuya Watanabe, Fumio Inagaki, Mads Albertsen, Per H Nielsen, Kenneth H Nealson

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Chemical Antiquity in Metabolism.Accounts of chemical research · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shino SuzukiGeobiology and Astrobiology Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama, Japan. shino.suzuki@riken.jp.ORCID 0000-0003-2176-2103
Shun'ichi IshiiInstitute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star), Japan Agency for Marine and Earth Science and Technology (JAMSTEC), Yokosuka, Kanagawa, Japan. sishii@jamstec.go.jp.ORCID 0000-0002-0203-8569
Grayson L ChadwickDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Yugo TanakaSchool of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Atsushi KouzumaSchool of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.ORCID 0000-0002-5076-3810
Kazuya WatanabeSchool of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
Fumio InagakiAdvanced Institute for Marine Ecosystem Change (WPI-AIMEC), JAMSTEC, Yokohama, Kanagawa, Japan.ORCID 0000-0003-2887-6525
Mads AlbertsenCenter for Microbial Communities, Aalborg University, Aalborg, Denmark.ORCID 0000-0002-6151-190X
Per H NielsenCenter for Microbial Communities, Aalborg University, Aalborg, Denmark.ORCID 0000-0002-6402-1877
Kenneth H NealsonDepartment of Earth Sciences, University of Southern California, Los Angeles, CA, USA.

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 20H04620MEXT | Japan Society for the Promotion of Science (JSPS) 22H05152MEXT | JST | Core Research for Evolutional Science and Technology (CREST) JPMJCR20S4
6 · The paper itself

Abstract

Serpentinization, a geochemical process found on modern and ancient Earth, provides an ultra-reducing environment that can support microbial methanogenesis and acetogenesis. Several groups of archaea, such as the order Methanocellales, are characterized by their ability to produce methane. Here, we generate metagenomic sequences from serpentinized springs in The Cedars, California, and construct a circularized metagenome-assembled genome of a Methanocellales archaeon, termed Met12, that lacks essential methanogenesis genes. The genome includes genes for an acetyl-CoA pathway, but lacks genes encoding methanogenesis enzymes such as methyl-coenzyme M reductase, heterodisulfide reductases and hydrogenases. In situ transcriptomic analyses reveal high expression of a multi-heme c-type cytochrome, and heterologous expression of this protein in a model bacterium demonstrates that it is capable of accepting electrons. Our results suggest that Met12, within the order Methanocellales, is not a methanogen but a CO

Indexed as

MethaneAcetyl Coenzyme AArchaeal ProteinsCarbon DioxideGenome, ArchaealMetagenomeMetagenomicsOxidoreductasesPhylogenyAcetyl Coenzyme AArchaeal ProteinsCarbon Dioxideheterodisulfide reductaseMethanemethyl coenzyme M reductaseOxidoreductases

Identifiers

PMID38871712
PMCPMC11176372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.