Evidence map›Paper›PMID 38871454›Full record

ArticleSexually transmitted infections2024

Risk factors for curable sexually transmitted infections among youth: findings from the STICH population survey in Zimbabwe.

Kevin Martin, Ethel Dauya, Victoria Simms, Tsitsi Bandason, Steven Azizi, Anna Machiha, Tinei Shamu, Primrose Musiyandaka, Tinashe Mwaturura, Suzanna C Francis and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Sexually transmitted infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03719521 (Community Based Interventions to Improve HIV Outcomes in Youth), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03719521 nacompletednot on this map

Community Based Interventions to Improve HIV Outcomes in Youth: a Cluster Randomised Trial in Zimbabwe (CHIEDZA)

TypeinterventionalSponsorLondon School of Hygiene and Tropical MedicineRan2019 to 2022Enrolled36,991ConditionsHIV InfectionArmsCommunity-based package of integrated HIV, SRH and general health services
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kevin MartinClinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK Kevin.Martin@lshtm.ac.uk.ORCID 0000-0001-6561-1353
Ethel DauyaThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Victoria SimmsThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Tsitsi BandasonThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.ORCID 0000-0003-0066-8345
Steven AziziThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Anna MachihaAIDS and TB Unit, Zimbabwe Ministry of Health and Child Care, Harare, Zimbabwe.
Tinei ShamuNewlands Clinic, Harare, Zimbabwe.
Primrose MusiyandakaThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Tinashe MwatururaThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Suzanna C FrancisMRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.
Constance R S Mackworth-YoungThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Joanna BuszaDepartment of Public Health, Environments and Society, The London School of Hygiene & Tropical Medicine, London, UK.
Constancia MavodzaThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Mandi TemboThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Richard J HayesMRC International Statistics and Epidemiology Group, Department of Infectious Disease Epidemiology, The London School of Hygiene & Tropical Medicine, London, UK.
Katharina KranzerClinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK.
Rashida A FerrandClinical Research Department, The London School of Hygiene & Tropical Medicine, London, UK.
Chido Dziva ChikwariThe Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesYouth are at high risk of sexually transmitted infections (STIs) in Africa. We aimed to determine the risk factors for curable STIs in youth in Zimbabwe.

methodsA population-based survey was conducted among randomly selected 18-24 year-olds in 16 communities across two provinces in Zimbabwe to ascertain outcomes for a cluster randomised trial investigating the impact of community-based STI screening for youth on population prevalence of STIs. Participants underwent an interviewer-administered questionnaire, HIV testing and screening for

resultsOf the 5601 participants, 62.5% (n=3500) were female, and the median age was 20 (IQR 19-22) years. HIV prevalence was 6.3% (351/5556), and 55.4% (1939/3501) reported condomless sex at last intercourse. Only 7.2% (401/5599) reported STI symptoms, but CT/NG/TV prevalence was 19.8% (1107/5601). On multivariable analysis, factors associated with STI diagnosis included being aged 21-24 years (adjusted OR (aOR) 1.37, 95% CI 1.17 to 1.61); female sex (aOR 2.11, 95% CI 1.76 to 2.53); being unemployed/informally employed (compared with in education/formal employment) (aOR 1.35, 95% CI 1.13 to 1.61); increasing number of sexual partners in the preceding 12 months (one partner: aOR 2.23, 95% CI 1.73 to 2.88; two partners: aOR 2.39, 95% CI 1.69 to 3.39); living with HIV (aOR 1.44, 95% CI 1.07 to 1.94); and previous attempted suicide (aOR 1.58, 95% CI 1.08 to 2.32).

conclusionsThe prevalence of STIs among youth in Zimbabwe is high, particularly among those with HIV. In addition to moving away from syndromic STI management and strengthening implementation of existing prevention tools, there is a need for a more holistic focus on broader risk factors such as mental health and employment opportunities, and of integration of HIV and STI programming. TRIAL REGISTRATION NUMBER: ISRCTN15013425, NCT03719521.

Indexed as

Sexually Transmitted DiseasesAdolescentChlamydia InfectionsFemaleGonorrheaHIV InfectionsHumansMalePrevalenceRandomized Controlled Trials as TopicRisk FactorsSexual BehaviorSurveys and QuestionnairesYoung AdultZimbabweAFRICAChlamydia InfectionsGonorrheaRisk factorsTRICHOMONAS

Identifiers

PMID38871454
PMCPMC11671898

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.