Evidence map›Paper›PMID 38869257›Full record

ReviewAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists2024

Parenteral nutrition in clinical practice: International challenges and strategies.

Paul E Wischmeyer, Stanislaw Klek, Mette M Berger, David Berlana, Brenda Gray, Joe Ybarra, Phil Ayers

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Analysis of factors driving variations in neonatal parenteral nutrition over a decade: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
  3. Observational
  4. Parenteral Nutrition in Eating Disorders: A Systematic Scoping Review.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. International Safety and Quality of Parenteral Nutrition Summit: Introduction.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024
    Article
  11. Safety and quality of parenteral nutrition: Areas for improvement and future perspectives.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paul E WischmeyerDepartment of Anesthesiology and Surgery, Duke University School of Medicine, Durham, NC, USA.
Stanislaw KlekSurgical Oncology Clinic, The Maria Sklodowska-Curie National Cancer Institute, Krakow, Poland.
Mette M BergerService of Adult Intensive Care, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
David BerlanaPharmacy Service, Vall d'Hebron Barcelona Hospital Campus and Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.
Brenda GrayClinical Pharmacy Partners, Tampa, FL, USA.
Joe YbarraSteward Health Care, Dallas, TX, USA.
Phil AyersClinical Pharmacy Services, Department of Pharmacy, Baptist Medical Center, Jackson, MS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeParenteral nutrition (PN) is an established therapy when oral/enteral feeding is not sufficient or is contraindicated, but nevertheless PN remains a complex, high-alert medication that is susceptible to errors that may affect patient safety. Over time, considerable progress has been made to make PN practices safer. The purpose of this article is to address ongoing challenges to improve the PN use process from prescription to administration and monitoring, and to outline practical aspects fostering the safety, quality, and cost-effectiveness of PN, as discussed at the International Safety and Quality of PN Summit. SUMMARY: Opportunities to improve the PN use process in clinical practice include the promotion of inter-disciplinary communication, vigilant surveillance for complications, staff education to increase competency, and more consistent use of advanced technologies that allow automated safety checks throughout the PN process. Topics covered include considerations on PN formulations, including the value of intravenous lipid emulsions (ILEs), trends in compounding PN, the current and future role of market-authorized multi-chamber PN bags containing all 3 macronutrients (amino acids, glucose/dextrose, and ILE) in the United States and in Europe, and strategies to cope with the increasing global problem of PN product shortages.

conclusionThis review outlines potential strategies to use in clinical practice to overcome ongoing challenges throughout the PN use process, and ultimately promote PN patient safety.

Indexed as

Parenteral NutritionEuropeFat Emulsions, IntravenousHumansInternationalityPatient SafetyUnited StatesFat Emulsions, Intravenouscompoundinglipidsmulti-chamber bagsParenteral nutritionpreparationproduct shortagessafety

Identifiers

PMID38869257
PMCPMC11170506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.