Evidence map›Paper›PMID 38869010›Full record

ArticleRenal failure2024

Decrease in platelet count in patients with AKI and its association with major adverse kidney events.

Ramón Medina-González, Jose J Zaragoza, Eduardo M Hernández-Barajas, Juarez Correa-de Leon, Rolando Claure-Del Granado, Armando Vazquez-Rangel, Liliana M Pineda-Segura, Martha K Franco-Garcia, Gael Chávez-Alonso, Juan A Gómez-Fregoso and 7 more

Abstract read
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
  6. Article
  7. Acute Kidney Injury (AKI) in Adults With Leukemia: A Nationwide Inpatient Retrospective Analysis.Journal of community hospital internal medicine perspectives · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ramón Medina-GonzálezNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.ORCID 0000-0002-7094-6964
Jose J ZaragozaIntensive Care Unit, Hospital H + Queretaro, Mexico.ORCID 0000-0003-0110-0794
Eduardo M Hernández-BarajasNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Juarez Correa-de LeonNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Rolando Claure-Del GranadoDivision of Nephrology, Hospital Obrero No 2 - CNS. IIBISMED, Facultad de Medicina, Universidad Mayor de San Simon, Cochabamba, Bolivia.
Armando Vazquez-RangelDepartment of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Liliana M Pineda-SeguraUniversity of Guadalajara Health Sciences Center, Guadalajara, Jalisco, Mexico.
Martha K Franco-GarciaUniversity of Guadalajara Health Sciences Center, Guadalajara, Jalisco, Mexico.
Gael Chávez-AlonsoUniversity of Guadalajara Health Sciences Center, Guadalajara, Jalisco, Mexico.
Juan A Gómez-FregosoNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Francisco G Rodríguez-GarcíaNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Guillermo Navarro-BlackallerNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.ORCID 0000-0003-0207-7135
Luz Alcantar-VallinNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.ORCID 0000-0002-6869-2387
Alejandro Martínez Gallardo-GonzálezNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Gabriela J Abundis-MoraNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Guillermo García-GarcíaUniversity of Guadalajara Health Sciences Center, Guadalajara, Jalisco, Mexico.ORCID 0000-0003-0558-0035
Jonathan S Chávez-IñiguezNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.ORCID 0000-0003-2786-6667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA reduction in platelet count in critically ill patients is a marker of severity of the clinical condition. However, whether this association holds true in acute kidney injury (AKI) is unknown. We analyzed the association between platelet reduction in patients with AKI and major adverse kidney events (MAKE).

methodsIn this retrospective cohort, we included AKI patients at the Hospital Civil of Guadalajara, in Jalisco, Mexico. Patients were divided according to whether their platelet count fell >21% during the first 10 days. Our objectives were to analyze the associations between a platelet reduction >21% and MAKE at 10 days (MAKE10) or at 30-90 days (MAKE30-90) and death.

resultsFrom 2017 to 2023, 400 AKI patients were included, 134 of whom had

conclusionIn our retrospective cohort of patients with AKI,

Indexed as

Acute Kidney InjuryAdultAgedCritical IllnessFemaleHumansMaleMexicoMiddle AgedPlatelet CountRenal DialysisRetrospective StudiesRisk FactorsThrombocytopeniaAcute kidney injuryhemodialysismajor adverse kidney eventsplateletsthrombocytopenia

Identifiers

PMID38869010
PMCPMC11177710

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.