Evidence map›Paper›PMID 38868965›Full record

ArticleCroatian medical journal2024

Pregnant couples' attitude toward extended pre-conceptional genomic screening.

Mojca Čižek Sajko, Bernarda Prosenc, Lovro Vidmar, Gordana Njenjić, Paula Duff, Borut Peterlin

Abstract read
In one paragraph

Article in Croatian medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mojca Čižek Sajko *
Bernarda Prosenc *
Lovro Vidmar
Gordana Njenjić
Paula Duff
Borut PeterlinBorut Peterlin, Clinical Institute for Genomic Medicine, University Medical Center Ljubljana, Šlajmerjeva 4, 1000 Ljubljana, Slovenia, borut.peterlin@kclj.si.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the attitudes of pregnant couples toward carrier screening genomic tests.

methodsA validated 22-item questionnaire was offered in person by medical staff to pregnant women ≥32 weeks' gestation and their partners attending prenatal classes from May to July 2014. The questionnaire inquired about demographic data, interest in various forms of genetic carrier screening tests, and genetic literacy.

resultsOf 497 respondents, 69% expressed strong interest in carrier screening. The interested respondents exhibited substantial support for screening for common (82%) or all known genetic diseases (79%), as well as for treatable (79%) and untreatable diseases (85%). The majority of respondents believed that genetic test results could provide them with a sense of security but also provoke anxiety and fear. They were aware that these results could affect their perspective on life, work, and the atmosphere within their family, and acknowledged the potential effect on their relationship with their partner. However, none of these concerns diminished their desire to learn about their carrier status. Respondents with higher genetic literacy exhibited greater interest in screening tests (P=0.006). More non-religious respondents compared with practicing religious respondents (P=0.002), and more respondents with higher education compared with those with lower education, expressed interest in screening (P=0.003).

conclusionMost respondents expressed considerable interest in receiving information about their carrier status through genetic tests.

Indexed as

Genetic TestingAdultFemaleGenetic Carrier ScreeningHealth Knowledge, Attitudes, PracticeHumansMalePregnancyPrenatal DiagnosisSurveys and Questionnaires

Identifiers

PMID38868965
PMCPMC11157253

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.