Evidence map›Paper›PMID 38868837›Full record

ArticleNeurology. Clinical practice2024

Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke in Cancer Patients: A Single-Center Experience and Meta-Analysis.

Mohamed N Elmarawany, Islam El Malky, Sebastian Winklhofer, Mira Katan, Souvik Kar, Gerasimos Baltsavias

Abstract read
In one paragraph

Article in Neurology. Clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Cerebrovascular and Peripheral Vascular Complications in Cancer Patients.Current neurology and neuroscience reports · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohamed N ElmarawanyDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.ORCID https://orcid.org/0000-0003-2667-4874
Islam El MalkyDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.ORCID https://orcid.org/0000-0002-3092-2159
Sebastian WinklhoferDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.
Mira KatanDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.ORCID https://orcid.org/0000-0002-9265-8066
Souvik KarDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.ORCID https://orcid.org/0009-0003-5368-571X
Gerasimos BaltsaviasDepartment of Neuroradiology (MNE, IEM, SW, MK, GB), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; Department of Neurosurgery (MNE), Faculty of Medicine, Menoufia University; Department of Neurology (IEM), Faculty of Medicine, South valley University, Egypt; Department of Neurology (MK), Clinical Neuroscience Center, University Hospital Zurich, Switzerland; and International Neuroscience Institute (SK, GB), Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: The published data about mechanical thrombectomy (MT) in cancer patients is sparse. We present our institutional experience in this clinical scenario, and a meta-analysis. Methods: The baseline data, procedural data, clinical and radiological outcomes of MT were analyzed and compared among three groups of stroke patients: controls, patients with active malignancy (AM), and patients with history of malignancy (HOM). A meta-analysis of 12 studies was conducted to address the differences between controls and AM patients regarding selected outcomes. Results: The 3 groups (controls, AM, HOM) showed significant differences regarding previous history of stroke or TIA (7.8% vs 10.5% vs 38.5%, Discussion: Endovascular MT is technically successful and reasonably safe in treating AIS from LVO in active malignancy patients. However, the causes and implications of sICH require further investigation. Despite technical success, these patients experience poor clinical outcomes, and the long-term benefits of MT remain uncertain.

Identifiers

PMID38868837
PMCPMC11165561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.