Evidence map›Paper›PMID 38868767›Full record

ReviewFrontiers in immunology2024

Artificial intelligence and neoantigens: paving the path for precision cancer immunotherapy.

Alla Bulashevska, Zsófia Nacsa, Franziska Lang, Markus Braun, Martin Machyna, Mustafa Diken, Liam Childs, Renate König

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  5. Technical review of artificial intelligence in TCR-T therapy.Journal of the National Cancer Center · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alla BulashevskaHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.
Zsófia NacsaHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.
Franziska LangTRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany.
Markus BraunHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.
Martin MachynaHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.
Mustafa DikenTRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany.
Liam ChildsHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.
Renate KönigHost-Pathogen-Interactions, Paul-Ehrlich-Institut, Langen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunotherapy has witnessed rapid advancement in recent years, with a particular focus on neoantigens as promising targets for personalized treatments. The convergence of immunogenomics, bioinformatics, and artificial intelligence (AI) has propelled the development of innovative neoantigen discovery tools and pipelines. These tools have revolutionized our ability to identify tumor-specific antigens, providing the foundation for precision cancer immunotherapy. AI-driven algorithms can process extensive amounts of data, identify patterns, and make predictions that were once challenging to achieve. However, the integration of AI comes with its own set of challenges, leaving space for further research. With particular focus on the computational approaches, in this article we have explored the current landscape of neoantigen prediction, the fundamental concepts behind, the challenges and their potential solutions providing a comprehensive overview of this rapidly evolving field.

Indexed as

Antigens, NeoplasmArtificial IntelligenceImmunotherapyNeoplasmsPrecision MedicineAnimalsComputational BiologyHumansAntigens, Neoplasmartificial intelligencecancer immunotherapyimmunopeptidomicsneoantigen predictionprecision medicine

Identifiers

PMID38868767
PMCPMC11167095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.