Evidence map›Paper›PMID 38868726›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2023

Recurrent reactive hypoglycemia due to clozapine-induced glucose intolerance: A case report.

Fumihiko Kawai, Satsuki Watanabe, Hirotaka Ebihara, Naoki Shimizu, Shiori Oshima, Hiroshi Okai, Yoshiko Murata, Hisatoshi Arai, Koji Matsuo

Abstract readCase Reports
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fumihiko KawaiDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.ORCID 0009-0006-9352-6539
Satsuki WatanabeDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Hirotaka EbiharaDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Naoki ShimizuDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Shiori OshimaDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Hiroshi OkaiDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Yoshiko MurataDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Hisatoshi AraiDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.
Koji MatsuoDepartment of Psychiatry, Faculty of Medicine Saitama Medical University Saitama Japan.ORCID 0000-0002-2002-5526

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although diabetes is one of the most common side effects of clozapine, a medication for the treatment of schizophrenia, to the best of our knowledge no study exists on clozapine-induced glucose intolerance or hypoglycemia in patients with schizophrenia. Case Presentation: We report a case of schizophrenia with repeated reactive hypoglycemia due to abnormal glucose tolerance during clozapine treatment. During clozapine administration in patients with schizophrenia, it is necessary to monitor physical and psychiatric symptoms due to reactive hypoglycemia and hyperglycemia. If abnormal glucose tolerance is a concern, it should be promptly detected using blood or oral glucose tolerance tests. Conclusion: Early intervention for impaired glucose tolerance may prevent clozapine discontinuation due to diabetes or hyperglycemia.

Indexed as

diabetesimpaired glucose toleranceinsulinoral glucose tolerance testvoglibose

Identifiers

PMID38868726
PMCPMC11114382

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.