Evidence map›Paper›PMID 38868710›Full record

ArticleiMeta2022

StrainPanDA: Linked reconstruction of strain composition and gene content profiles via pangenome-based decomposition of metagenomic data.

Han Hu, Yuxiang Tan, Chenhao Li, Junyu Chen, Yan Kou, Zhenjiang Zech Xu, Yang-Yu Liu, Yan Tan, Lei Dai

Abstract read
In one paragraph

Article in iMeta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Orally administratedFrontiers in immunology · 2023
    Trial
  2. Article
  3. Article
  4. Article
  5. Quantifying Metagenomic Strain Associations from Microbiomes with Anpan.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Han HuCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen China.
Yuxiang TanCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen China.
Chenhao LiCenter for Computational and Integrative Biology Massachusetts General Hospital and Harvard Medical School, Richard B. Simches Research Center Boston Massachusetts USA.
Junyu ChenCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen China.
Yan KouBioinformatics Department Xbiome, Scientific Research Building, Tsinghua High-Tech Park Shenzhen China.
Zhenjiang Zech XuDepartment of Food Science and Technology, State Key Laboratory of Food Science and Technology Nanchang University Nanchang China.
Yang-Yu LiuChanning Division of Network Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts USA.
Yan TanBioinformatics Department Xbiome, Scientific Research Building, Tsinghua High-Tech Park Shenzhen China.
Lei DaiCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences Shenzhen China.ORCID 0000-0002-5598-5308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial strains of variable functional capacities coexist in microbiomes. Current bioinformatics methods of strain analysis cannot provide the direct linkage between strain composition and their gene contents from metagenomic data. Here we present

Indexed as

gene content profilemetagenomicsmicrobiomepangenomestrain analysis

Identifiers

PMID38868710
PMCPMC10989911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.