Evidence map›Paper›PMID 38868671›Full record

ArticleJournal of arthropod-borne diseases2023

Anti-Leishmanial Effects of a Novel Biocompatible Non-Invasive Nanofibers Containing Royal Jelly and Propolis against Iranian Strain of

Mohsen Mahmoudi, Bita Mehravi, Mohammad Shabani, Ramtin Hadighi, Alireza Badirzadeh, Ahmad Dehdast, Ghazale Chizari-Fard, Vahid Pirhajati-Mahabadi, Sekineh Akbari, Fatemeh Tabatabaie and 1 more

Abstract read
In one paragraph

Article in Journal of arthropod-borne diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Efficacy of a Hemolymph-Based Cream Derived fromJournal of arthropod-borne diseases · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohsen MahmoudiDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Bita MehraviDepartment of Medical Nanotechnology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mohammad ShabaniDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ramtin HadighiDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Alireza BadirzadehDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ahmad DehdastDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ghazale Chizari-FardDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Vahid Pirhajati-MahabadiNeuroscience Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sekineh AkbariDepartment of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Fatemeh TabatabaieDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mehdi MohebaliDepartment of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current medications especially the pentavalent antimonial compounds have been used as the first line treatment of cutaneous leishmaniasis (CL), but they have limitations due to serious side effects such as drug resistance, cardio and nephrotoxicity, and high costs. Hence, the demand to find more usable drugs is evident. Synthesis and development of natural, effective, biocompatible, and harmless compounds against Methods: By electrospinning method, a new type of nanofiber were synthesized from royal jelly and propolis with different ratios. Nanofibers were characterized by Scanning Electron Microscope (SEM), Transmission Electron Microscopy (TEM), Thermogravimetric Analysis (TGA), Contact angle, and Fourier-transform infrared spectroscopy (FTIR). The Half-maximal inhibitory concentration (IC Results: The results showed that the proposed formulas provide a new achievement that, despite the significant killing activity on Conclusion: This study presents a great challenge to introduce a new low-cost treatment method for CL, accelerate wound healing, and reduce scarring with minimal side effects and biocompatible materials. Royal jelly and propolis nanofibers significantly inhibit the growth of

Indexed as

In-vitroLeishmania majorNanofiberPropolisRoyal jelly

Identifiers

PMID38868671
PMCPMC11164616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.