Evidence map›Paper›PMID 38868537›Full record

ArticleHealth science reports2024

Left anterior descending coronary artery-left circumflex coronary artery bifurcation angle and severity of coronary artery disease; is there any correlation? A cross-sectional study.

Pejman Mansouri, Ebrahim Nematipour, Nadia Rajablou, Seyyed Mojtaba Ghorashi, Samad Azari, Negar Omidi

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Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pejman MansouriTehran Heart Center, Cardiovascular Disease Research Institute Tehran University of Medical Sciences Tehran Iran.ORCID 0000-0001-6407-0241
Ebrahim NematipourTehran Heart Center, Cardiovascular Disease Research Institute Tehran University of Medical Sciences Tehran Iran.
Nadia RajablouSchool of Medicine Tehran University of Medical Sciences Tehran Iran.ORCID 0000-0002-6228-8447
Seyyed Mojtaba GhorashiTehran Heart Center, Cardiovascular Disease Research Institute Tehran University of Medical Sciences Tehran Iran.ORCID 0000-0002-7933-5633
Samad AzariHospital Management Research Center, Health Management Research Institute Iran University of Medical Sciences Tehran Iran.ORCID 0000-0003-2781-7793
Negar OmidiCardiovascular Imaging Departement, Tehran Heart Center, School of Medicin, Tehran University of Medical Sciences Tehran heart center Tehran Iran.ORCID 0000-0003-2344-1661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: The aim of this study is to evaluate the association of coronary computed tomography angiography derived (CCTA) plaque characteristics and the left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX) bifurcation angle with severity of coronary artery disease (CAD). Methods: All the stable patients with suspected CAD who underwent CCTA between January to December 2021 were included. Correlation between CCTA-derived aggregated plaque volume (APV), LAD-LCX angle, remodeling index (RI), coronary calcium score with Gensini score in conventional angiography were assessed. One hundred and twenty-two patients who underwent both CCTA and coronary angiography were analyzed. Results: Our analysis showed that the median (percentile 25% to percentile 75%) of the APV, LAD-LCx angle, and calcium score were 31% (17%-47%), 58° (39°-89°), and 31 (0-186), respectively. Also, the mean ± SD of the RI was 1.05 ± 0.20. Significant correlation between LAD-LCx bifurcation angle (0.0001-0.684), APV (0.002-0.281), RI (0.0001-0.438), and calcium score (0.016-0.217) with Gensini score were detected. There was a linear correlation between the mean LAD-LCx bifurcation angle and the Gensini score. The sensitivity and specificity for the cut-off value of 47.5° for the LAD-LCX angle were 86.7% and 82.1%, respectively. Conclusion: There is a direct correlation between the LAD-LCx angle and the Gensini score. In addition to plaque characteristics, anatomic-based CCTA-derived indices can be used to identify patients at higher risk for CAD.

Indexed as

bifurcation anglecalcium scorecoronary artery diseasecoronary computed tomography angiographyGensini score

Identifiers

PMID38868537
PMCPMC11168269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.