Evidence map›Paper›PMID 38868334›Full record

ReviewiMeta2023

New insights into the mechanisms of high-fat diet mediated gut microbiota in chronic diseases.

Jiali Chen, Yuhang Xiao, Dongmei Li, Shiqing Zhang, Yingzi Wu, Qing Zhang, Weibin Bai

Abstract readReview
In one paragraph

Review in iMeta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Dietary Supplementation withAnimals : an open access journal from MDPI · 2026
    Article
  8. Foods (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Effects and mechanism ofWorld journal of gastroenterology · 2026
    Article
  18. Marine life science & technology · 2026
    Article
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiali ChenDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection Jinan University Guangzhou China.ORCID 0000-0002-7317-4146
Yuhang XiaoDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection Jinan University Guangzhou China.
Dongmei LiDepartment of Microbiology & Immunology Georgetown University Medical Center Washington District of Columbia USA.
Shiqing ZhangJNU-HKUST Joint Laboratory for Neuroscience and Innovative Drug Research, College of Pharmacy Jinan University Guangzhou China.
Yingzi WuSchool of Chinese Medicine, Centre for Cancer and Inflammation Research Hong Kong Baptist University Hong Kong China.
Qing ZhangDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection Jinan University Guangzhou China.
Weibin BaiDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Guangdong Engineering Technology Center of Food Safety Molecular Rapid Detection Jinan University Guangzhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-fat diet (HFD) has been recognized as a primary factor in the risk of chronic disease. Obesity, diabetes, gastrointestinal diseases, neurodegenerative diseases, and cardiovascular diseases have long been known as chronic diseases with high worldwide incidence. In this review, the influences of gut microbiota and their corresponding bacterial metabolites on the mechanisms of HFD-induced chronic diseases are systematically summarized. Gut microbiota imbalance is also known to increase susceptibility to diseases. Several studies have proven that HFD has a negative impact on gut microbiota, also exacerbating the course of many chronic diseases through increased populations of

Indexed as

characteristic metaboliteschronic diseasesgut microbiota dysbiosishigh‐fat diettargeted biomarkers

Identifiers

PMID38868334
PMCPMC10989969

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.