Evidence map›Paper›PMID 38868174›Full record

ArticleCritical care research and practice2024

Retrospective Tertiary Care-Based Cohort Study on Clinical Characteristics and Outcomes of Ceftazidime-Avibactam-Resistant Carbapenem-Resistant

Fatema Ahmed, Betsy Abraham, Nermin Kamal Saeed, Hasan Mohamed Naser, Kannan Sridharan

Abstract read
In one paragraph

Article in Critical care research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Ceftazidime-Avibactam Resistance in Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatema AhmedDepartment of Intensive Care, Salmaniya Medical Complex, Manama, Bahrain.ORCID https://orcid.org/0009-0006-2348-0344
Betsy AbrahamDepartment of Intensive Care, Salmaniya Medical Complex, Manama, Bahrain.ORCID https://orcid.org/0000-0002-9868-6893
Nermin Kamal SaeedDepartment of Microbiology, Salmaniya Medical Complex, Manama, Bahrain.
Hasan Mohamed NaserDepartment of Intensive Care, Ibn Al Nafees Hospital, Manama, Bahrain.
Kannan SridharanDepartment of Pharmacology and Therapeutics, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.ORCID https://orcid.org/0000-0003-3811-6503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The advent of ceftazidime-avibactam (CAZ-AVI)-resistant carbapenem-resistant Methods: The study retrospectively examined the clinical and microbiological data of patients with ceftazidime avibactam susceptible and ceftazidime avibactam-resistant Results: A total of 152 patients with CRKP infection were enrolled in this study. Patients with CAZ-AVI-resistant CRKP isolates (20/34 = 58.8%) had prior exposure to carbapenems ( Conclusion: Early advent of CAZ-AVI resistance in CRE isolates highlights the dynamic necessity of routine CAZ-AVI resistance laboratory testing and antimicrobial stewardship programmes focusing on the utilization of all antibiotics. Consolidating the hospital infection control of tracheostomies may help to prevent CAZ resistance in CRKP. Colistin may aid in decreasing of mortality rates among patients with CAZ-AVI CRKP isolates.

Identifiers

PMID38868174
PMCPMC11168800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.