Evidence map›Paper›PMID 38867918›Full record

ReviewOrthopaedic journal of sports medicine2024

Clinical Results of Primary Repair Versus Reconstruction of the Anterior Cruciate Ligament: A Systematic Review and Meta-analysis of Contemporary Trials.

Kyle N Kunze, Ayoosh Pareek, Benedict U Nwachukwu, Anil S Ranawat, Andrew D Pearle, Bryan T Kelly, Answorth A Allen, Riley J Williams

Registry-linked trialAbstract readReview
In one paragraph

Review in Orthopaedic journal of sports medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07318272 (Comparison of Clinical and Functional Outcomes After Anterior Cruciate Ligament Reconstruction and Primary Repair Surgery), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07318272 recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Clinical and Functional Outcomes After Anterior Cruciate Ligament Reconstruction and Primary Repair Surgery

TypeobservationalSponsorGazi UniversityRan2026 to 2027Enrolled45ConditionsAnterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Postcommercialisation outcomes of bridge-enhanced anterior cruciate ligament restoration: The first 100 Bridge registry patients.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyle N KunzeDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.ORCID https://orcid.org/0000-0002-0363-3482
Ayoosh PareekDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Benedict U NwachukwuDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Anil S RanawatDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.ORCID https://orcid.org/0000-0002-3634-4871
Andrew D PearleDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Bryan T KellyDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Answorth A AllenDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Riley J WilliamsDepartment of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.ORCID https://orcid.org/0000-0003-2991-7173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary anterior cruciate ligament (ACL) repair has gained renewed interest in select centers for patients with proximal or midsubstance ACL tears. Therefore, it is important to reassess contemporary clinical outcomes of ACL repair to determine whether a clinical benefit exists over the gold standard of ACL reconstruction (ACLR). Purpose: To (1) perform a meta-analysis of comparative trials to determine whether differences in clinical outcomes and adverse events exist between ACL repair versus ACLR and (2) synthesize the midterm outcomes of available trials. Study Design: Systematic review; Level of evidence, 3. Methods: The PubMed, OVID/Medline, and Cochrane databases were queried in August 2023 for prospective and retrospective clinical trials comparing ACL repair and ACLR. Data pertaining to tear location, surgical technique, adverse events, and clinical outcome measures were recorded. DerSimonian-Laird random-effects models were constructed to quantitatively evaluate the association between ACL repair/ACLR, adverse events, and clinical outcomes. A subanalysis of minimum 5-year outcomes was performed. Results: Twelve studies (893 patients; 464 ACLR and 429 ACL repair) were included. Random-effects models demonstrated a higher relative risk (RR) of recurrent instability/clinical failure (RR = 1.64; 95% confidence interval [CI], 1.04-2.57; Conclusion: In contemporary comparative trials of ACL repair versus ACLR, the RR of clinical failure, revision surgery due to ACL rerupture, and hardware removal was greater for primary ACL repair compared with ACLR. There were no observed differences in patient-reported outcome scores, reoperations, or knee-related complications between approaches. In the limited literature reporting on minimum 5-year outcomes, significant differences in adverse events or the International Knee Documentation Committee score were not observed.

Indexed as

adverse eventsanterior cruciate ligamentpatient-reported outcomesreconstructionrepair

Identifiers

PMID38867918
PMCPMC11168252

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.