Evidence map›Paper›PMID 38867868›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2024

The role of sodium-glucose co-transporter 2 inhibitors in myocardial infarction: available evidence and future perspectives.

Giovanni Amedeo Tavecchia, Elena Gualini, Alice Sacco, Fabrizio Oliva

Abstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovanni Amedeo TavecchiaASST Great Metropolitan Niguarda, Milan.
Elena GualiniASST Great Metropolitan Niguarda, Milan.
Alice SaccoASST Great Metropolitan Niguarda, Milan.
Fabrizio OlivaASST Great Metropolitan Niguarda, Milan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an unmet need for new treatment options for patients with acute myocardial infarction (AMI) as progress in patients' outcomes has plateaued over the past 15 years. Sodium-glucose co-transporter 2 (SGLT2) inhibitors have demonstrated cardio-renal benefits in various disease states, encompassing diabetes mellitus, chronic kidney disease, and heart failure. Experimental studies further support their use in AMI, demonstrating beneficial effects in animal models by reducing infarct size and mitigating adverse cardiac remodelling. Recently, two clinical trials have been published thus paving the way for a new field to explore. This paper briefly outlines the available evidence and future perspectives regarding the use of SGLT2 inhibitors in this clinical scenario.

Indexed as

Acute myocardial infarctionCardiovascular outcomesSodium–glucose co-transporter 2 inhibitors

Identifiers

PMID38867868
PMCPMC11167973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.