Evidence map›Paper›PMID 38867856›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2024

Ablation of the epicardial substrate in patients with long-QT syndrome at risk of sudden death.

Carlo Pappone, Antonio Boccellino, Giuseppe Ciconte, Luigi Anastasia

Abstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carlo PapponeArrhythmia and Electrophysiology Center, IRCCS Policlinico San Donato, San Donato Milanese, Milan.
Antonio BoccellinoArrhythmia and Electrophysiology Center, IRCCS Policlinico San Donato, San Donato Milanese, Milan.
Giuseppe CiconteArrhythmia and Electrophysiology Center, IRCCS Policlinico San Donato, San Donato Milanese, Milan.
Luigi AnastasiaVita-Salute San Raffaele University, Milan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sudden cardiac death remains a critical public health concern globally, affecting millions annually. Recent advances in cardiac arrhythmia mapping have demonstrated that the ventricular epicardial region has a critical arrhythmogenic role in some inherited cardiogenetic diseases. Among these, long-QT syndrome (LQTS) exposes patients to the risk of life-threatening arrhythmic events. Despite advancements, there is a need for more effective therapeutic strategies. A recent study has uncovered a noteworthy connection between LQTS and epicardial structural abnormalities, challenging the traditional view of LQTS as purely an electrical disorder. High-density mapping revealed electroanatomic abnormalities in the right ventricular epicardium, presenting a potential target for catheter ablation, to finally suppress ventricular fibrillation recurrences in high-risk LQTS patients.

Indexed as

Arrhythmogenic substrateEpicardiumLong-QT syndromeMalignant arrhythmiasRadiofrequency ablationVentricular fibrillation

Identifiers

PMID38867856
PMCPMC11167969

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.