Evidence map›Paper›PMID 38867824›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2023

Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case-control study.

Chihiro Morishita, Jiro Masuya, Yoshitaka Ishii, Tomoteru Seki, Ayaka Deguchi, Yoshio Iwata, Yu Tamada, Yota Fujimura, Mina Honyashiki, Kazuharu Harada and 2 more

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chihiro MorishitaDepartment of Psychiatry Tokyo Medical University Tokyo Japan.ORCID 0000-0002-8480-9303
Jiro MasuyaDepartment of Psychiatry Tokyo Medical University Tokyo Japan.
Yoshitaka IshiiDepartment of Psychiatry Tokyo Medical University Tokyo Japan.
Tomoteru SekiDepartment of Psychiatry Tokyo Medical University Tokyo Japan.ORCID 0000-0003-2593-7118
Ayaka DeguchiDepartment of Psychiatry Tokyo Medical University Tokyo Japan.
Yoshio IwataDepartment of Psychiatry Tokyo Medical University Tokyo Japan.
Yu TamadaDepartment of Psychiatry Tokyo Medical University Hachioji Medical Center Tokyo Japan.
Yota FujimuraDepartment of Psychiatry Tokyo Medical University Hachioji Medical Center Tokyo Japan.
Mina HonyashikiDepartment of Psychiatry Tokyo Medical University Tokyo Japan.
Kazuharu HaradaDepartment of Health Data Science Tokyo Medical University Tokyo Japan.
Masataka TaguriDepartment of Health Data Science Tokyo Medical University Tokyo Japan.
Takeshi InoueDepartment of Psychiatry Tokyo Medical University Tokyo Japan.ORCID 0000-0001-5248-1289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients. Methods: A retrospective matched case-control study was conducted on adult patients admitted to every department of Tokyo Medical University Hospital, with the outcome being in-hospital falls. A total of 447 hospitalized patients who had had in-hospital falls at some point in their hospitalization between January 2016 and December 2016 were included as cases. A total of 447 hospitalized patients who did not have in-hospital falls, and were individually matched to the cases by sex, age, and clinical department, were included as controls. All data were extracted from electronic medical records. Conditional logistic regression analyses were conducted to assess the association between the exposure to 16 psychotropic medications and the occurrence of in-hospital falls. The multivariable logistic regression model adjusted sex, age, clinical department, body mass index, fall risk score on the fall risk assessment measure, and use of psychotropic medications. Results: The multivariable conditional logistic regression model showed a significant association between the use of risperidone (odds ratio [OR] = 3.730; 95% confidence interval [CI] = 1.229-11.325) and flunitrazepam (OR = 4.120; 95% CI = 1.105-15.364) and an increased OR of falls among hospitalized patients. Conclusion: The use of risperidone and flunitrazepam were identified as risk factors for falls among hospitalized patients.

Indexed as

fallshospitalized patientsmatched case–control studypsychotropicsrisk factor

Identifiers

PMID38867824
PMCPMC11114364

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