ArticleNature2024
DNA mismatch and damage patterns revealed by single-molecule sequencing.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed.
- Origins and timing of somatic variants in the brain.Current opinion in genetics & development · 2026Review
- Somatic mosaicism in the brain: linking development, ageing and neurodegeneration.Nature reviews. Neurology · 2026Review
- Article
- Methyltransferase-assisted single duplex sequencing for detecting circulating tumor DNA.EMBO molecular medicine · 2026Article
- High-fidelity rare structural variant detection with HiFiRE3 reduced representation via restriction enzyme ends.bioRxiv : the preprint server for biology · 2026Article
- Development of a multifunctional nucleic acid response platform utilizing the Cas12a and Cas13a integrated targeting system.Nucleic acids research · 2026Article
- Duplex-Indel: a Snakemake pipeline for somatic Indel calling in Tn5 transposase-based duplex sequencing data.Bioinformatics (Oxford, England) · 2026Article
- Disease insights from brain somatic mosaicism.Experimental & molecular medicine · 2026Review
- Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics.Nature communications · 2026Article
- Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.Regulatory toxicology and pharmacology : RTP · 2026Review
- Benchmarking of duplex sequencing approaches to reveal somatic mutation landscapes.bioRxiv : the preprint server for biology · 2025Article
- Reconstructing the lifelong history of cells and tissues via somatic mutation analysis.Cellular and molecular life sciences : CMLS · 2025Review
- The human mycobiome: a critical yet understudied component of health and disease.Microbiology (Reading, England) · 2025Review
- Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer.The Journal of pathology · 2025Article
- Somatic mutation and selection at population scale.Nature · 2025Article
- Article
- Advances in single-cell DNA sequencing enable insights into human somatic mosaicism.Nature reviews. Genetics · 2025Review
- Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy.Science (New York, N.Y.) · 2025Article
- Decoding information stored in DNAs through single-molecule electrical detection platforms.Innovation (Cambridge (Mass.)) · 2025Review
- Article
Corrections and comments
- Update of
Authors and funding
24 authors.
Mei Hong Liu *Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Benjamin M Costa *Center for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0009-0004-2320-090X
Emilia C BianchiniCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Una ChoiCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-2406-2594
Rachel C BandlerCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Emilie LassenCryos International Sperm and Egg Bank, Aarhus, Denmark.ORCID 0000-0002-1484-2028
Marta Grońska-PęskiCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-9965-8520
Adam SchwingCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Zachary R MurphyCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0003-3017-7248
Daniel RosenkjærCryos International Sperm and Egg Bank, Aarhus, Denmark.
Shany PicciottoDepartment of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Vanessa BianchiProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lucie StengsProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
Melissa EdwardsProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nuno Miguel NunesProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-3879-9757
Caitlin A LohCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Tina K TruongCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA.
Randall E BrandDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Tomi PastinenGenomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO, USA.ORCID 0000-0003-4016-5021
J Richard WagnerDepartment of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Anne-Bine SkytteCryos International Sperm and Egg Bank, Aarhus, Denmark.ORCID 0000-0002-0067-9557
Uri TaboriProgram in Genetics and Genome Biology, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-5019-2683
Jonathan E ShoagDepartment of Urology, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Gilad D EvronyCenter for Human Genetics and Genomics, New York University Grossman School of Medicine, New York, NY, USA. gilad.evrony@nyulangone.org.ORCID 0000-0001-7621-2630
Funding
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Richard Lewis Possemato · 1985 to 2026
$83.1MPostdoctoral Research Training in Neurodegenerative Disorders and the Aging BrainT32AG052909 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Helen E Scharfman, THOMAS M WISNIEWSKI · 2017 to 2026
$2.5MSingle-cell genomic approaches to study the cellular origins of brain tumorsDP5OD028158 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EVRONY, GILAD DAVID · 2019 to 2023
$2.1MUltra-High Fidelity Single-Molecule Profiling of Mosaic Double- and Single-Strand DNA Mutations and DamageUG3NS132024 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EVRONY, GILAD DAVID · 2023 to 2024
$859kDirect measurement of the male germline mutation rate using sequential sperm samplesR21HD105910 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EVRONY, GILAD DAVID, SHOAG, JONATHAN · 2021 to 2022
$479kThe PacBio Sequel for Single Molecule, Real-Time, Long Read SequencingS10OD023423 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HEGUY, ADRIANA · 2017 to 2017
$350kMeasurement of cell-type specific somatic mutation rates in the aging human brain - Resubmission – 1F32AG076287 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GRONSKA-PESKI, MARTA · 2022 to 2023
$139kNCI NIH HHS P30 CA016087NIA NIH HHS F32 AG076287NIA NIH HHS T32 AG052909NICHD NIH HHS R21 HD105910NIH HHS DP5 OD028158NIH HHS S10 OD023423NINDS NIH HHS UG3 NS132024
Abstract
Mutations accumulate in the genome of every cell of the body throughout life, causing cancer and other diseases
Indexed as
Base Pair MismatchDNA DamageDNA, Single-StrandedSequence Analysis, DNASingle Molecule ImagingAgingAPOBEC DeaminasesCytidine DeaminaseCytosineDeaminationDNA Mismatch RepairDNA ReplicationFemaleGenome, MitochondrialHumansMaleAPOBEC3A protein, humanAPOBEC DeaminasesCytidine DeaminaseCytosineDNA, Single-StrandedProteins
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.