ArticleNature2024
Strand-resolved mutagenicity of DNA damage and repair.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells.Oncology letters · 2026Article
- Widespread atypical UV-induced mutations form in single-stranded DNA.Science advances · 2026Article
- Article
- Two Faces of UV Mutagenesis: Independent and Collateral Mutagenesis in Skin Cancers.Life (Basel, Switzerland) · 2026Article
- Article
- Lock-Open: An AND Logic-Gated, Entropy-Driven DNA Nanowalker for Highly Sensitive Detection of UDG and APE1 Activities in Hepatocellular Carcinoma.Advanced healthcare materials · 2026Article
- High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution.Nature communications · 2026Article
- Mapping DNA glycosylase binding across lesion sequence contexts reveals extended sequence and structural recognition logic.Nature communications · 2026Article
- Bone regeneration using aged donor cells and visible light-curable hydrogel: An in vitro and in vivo evaluation.Journal of periodontology · 2026Article
- The aging genome exhibits organized vulnerability to somatic mutations.bioRxiv : the preprint server for biology · 2026Article
- Topographical archetypes of somatic mutagenesis in cancer.bioRxiv : the preprint server for biology · 2026Article
- Blood-based epigenetic instability linked to human aging and disease.Nature communications · 2026Article
- Interpreting cancer genetics through a two-step "evolutionary cascade hypothesis": bridging neutral and selective perspectives.Journal of translational medicine · 2026Review
- Conserved 3D genome reorganization during DNA repair.Life science alliance · 2026Review
- Overcoming Resistance to PARP Inhibitors in BRCA-Mutated Cancers: Mechanisms and Therapeutic Strategies.Journal of Cancer · 2026Review
- High-throughput characterization of transcription factors that modulate UV damage formation and repair at single-nucleotide resolution.Research square · 2025Article
- Combined pesticide pollution enhances the dissemination of the phage-encoded antibiotic resistome in the soil under nitrogen deposition.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Segregating DNA lesions point to high selective advantage of tumor initiating cells.bioRxiv : the preprint server for biology · 2025Article
- Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms.Nucleic acids research · 2025Article
- Residues in the little finger domain of the Y-family Dpo4 DNA polymerase communicate to restrict synthesis past 8-oxoguanine lesions.Nucleic acids research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Craig J AndersonMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Lana TalmaneMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Juliet LuftMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2458-9377
John ConnellyMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Michael D NicholsonCRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2813-8979
Jan C VerburgMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-3012-3015
Oriol PichInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Susan CampbellMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Marco GiaisiBrain Mosaicism and Tumorigenesis (B400), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pei-Chi WeiBrain Mosaicism and Tumorigenesis (B400), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Vasavi SundaramEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
Frances ConnorCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.ORCID 0000-0003-2858-9411
Paul A GinnoDivision of Regulatory Genomics and Cancer Evolution (B270), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Takayo SasakiSan Diego Biomedical Research Institute, San Diego, CA, USA.
David M GilbertSan Diego Biomedical Research Institute, San Diego, CA, USA.ORCID 0000-0001-8087-9737
Liver Cancer Evolution Consortium
Núria López-BigasInstitute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID 0000-0003-4925-8988
Colin A SempleMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Duncan T OdomCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. d.odom@dkfz-heidelberg.de.ORCID 0000-0001-6201-5599
Sarah J AitkenMedical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK. sa696@cam.ac.uk.ORCID 0000-0002-1897-4140
Martin S TaylorMedical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. martin.taylor@ed.ac.uk.ORCID 0000-0001-7656-330X
Funding
Genome Plasticity during ES Cell Differentiation to Neural LineagesR01GM083337 · NIGMS · SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE · PI David M Gilbert · 2007 to 2026
$6.1MCancer Research UK 20412Cancer Research UK 22398Medical Research Council MC_UU_00007/11Medical Research Council MC_UU_00035/2Medical Research Council MR/K001744/1NIGMS NIH HHS R01 GM083337Wellcome Trust
Abstract
DNA base damage is a major source of oncogenic mutations
Indexed as
DNADNA DamageDNA-Directed DNA PolymeraseDNA RepairMutagenesisMutationAlkylationAnimalsCell LineDNA AdductsDNA ReplicationHumansMiceNeoplasmsTranscription, GeneticUltraviolet RaysDNADNA AdductsDNA-Directed DNA Polymerase
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.