Evidence map›Paper›PMID 38867035›Full record

ArticleJapanese journal of radiology2024

Evaluating ChatGPT-4V in chest CT diagnostics: a critical image interpretation assessment.

Reza Dehdab, Andreas Brendlin, Sebastian Werner, Haidara Almansour, Sebastian Gassenmaier, Jan Michael Brendel, Konstantin Nikolaou, Saif Afat

Abstract read
In one paragraph

Article in Japanese journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Large Language Models in Lung Cancer: Systematic Review.Journal of medical Internet research · 2025
    Pooled it
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  6. Artificial superintelligence alignment in healthcare.Japanese journal of radiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reza DehdabDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany. reza.dehdab@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0002-3496-8808
Andreas BrendlinDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Sebastian WernerDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Haidara AlmansourDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Sebastian GassenmaierDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Jan Michael BrendelDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Konstantin NikolaouDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.
Saif AfatDepartment of Diagnostic and Interventional Radiology, Tuebingen University Hospital, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the diagnostic accuracy of ChatGPT-4V in interpreting a set of four chest CT slices for each case of COVID-19, non-small cell lung cancer (NSCLC), and control cases, thereby evaluating its potential as an AI tool in radiological diagnostics. MATERIALS AND

methodsIn this retrospective study, 60 CT scans from The Cancer Imaging Archive, covering COVID-19, NSCLC, and control cases were analyzed using ChatGPT-4V. A radiologist selected four CT slices from each scan for evaluation. ChatGPT-4V's interpretations were compared against the gold standard diagnoses and assessed by two radiologists. Statistical analyses focused on accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), along with an examination of the impact of pathology location and lobe involvement.

resultsChatGPT-4V showed an overall diagnostic accuracy of 56.76%. For NSCLC, sensitivity was 27.27% and specificity was 60.47%. In COVID-19 detection, sensitivity was 13.64% and specificity of 64.29%. For control cases, the sensitivity was 31.82%, with a specificity of 95.24%. The highest sensitivity (83.33%) was observed in cases involving all lung lobes. The chi-squared statistical analysis indicated significant differences in Sensitivity across categories and in relation to the location and lobar involvement of pathologies.

conclusionChatGPT-4V demonstrated variable diagnostic performance in chest CT interpretation, with notable proficiency in specific scenarios. This underscores the challenges of cross-modal AI models like ChatGPT-4V in radiology, pointing toward significant areas for improvement to ensure dependability. The study emphasizes the importance of enhancing these models for broader, more reliable medical use.

Indexed as

Carcinoma, Non-Small-Cell LungCOVID-19Lung NeoplasmsSensitivity and SpecificityTomography, X-Ray ComputedAgedFemaleHumansLungMaleMiddle AgedPandemicsRadiographic Image Interpretation, Computer-AssistedRadiography, ThoracicReproducibility of ResultsRetrospective StudiesAI (artificial intelligence)ChatGPT-4VComputed tomographyComputer-aided diagnosis (CAD)

Identifiers

PMID38867035
PMCPMC11442562

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.