Evidence map›Paper›PMID 38867019›Full record

ArticleNature materials2024

Stretchable ionic-electronic bilayer hydrogel electronics enable in situ detection of solid-state epidermal biomarkers.

Ruth Theresia Arwani, Sherwin Chong Li Tan, Archana Sundarapandi, Wei Peng Goh, Yin Liu, Fong Yew Leong, Weifeng Yang, Xin Ting Zheng, Yong Yu, Changyun Jiang and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Multiscale Manufacturing of Organic Electronic Materials.Advanced materials (Deerfield Beach, Fla.) · 2026
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  16. Chemical ONature communications · 2026
    Article
  17. Article
  18. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  19. Article
  20. Organoid Brain-Machine-Interface Devices for Central Nervous System Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Ruth Theresia ArwaniDepartment of Biomedical Engineering (BME), National University of Singapore, Singapore, Singapore.ORCID 0000-0002-0941-0132
Sherwin Chong Li TanInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-3835-0060
Archana SundarapandiDepartment of Biomedical Engineering (BME), National University of Singapore, Singapore, Singapore.ORCID 0009-0002-6053-367X
Wei Peng GohInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-7987-7950
Yin LiuInstitute of High-Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Fong Yew LeongInstitute of High-Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-0064-0118
Weifeng YangDepartment of Biomedical Engineering (BME), National University of Singapore, Singapore, Singapore.
Xin Ting ZhengInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-1431-0929
Yong YuInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-6271-707X
Changyun JiangInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-0655-3584
Yuan Ching AngDepartment of Biomedical Engineering (BME), National University of Singapore, Singapore, Singapore.
Lingxuan KongSchool of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, Singapore, Singapore.
Siew Lang TeoInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0001-8938-2495
Peng ChenSchool of Chemistry, Chemical Engineering and Biotechnology (CCEB), Nanyang Technological University, Singapore, Singapore.ORCID 0000-0003-3730-1846
Xinyi SuDepartment of Ophthalmology, Yong Loo Lin School of Medicine, Singapore, Singapore.
Hongying LiInstitute of High-Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0003-4736-295X
Zhuangjian LiuInstitute of High-Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-3412-2116
Xiaodong ChenInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-3312-1664
Le YangInstitute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. yang_le@imre.a-star.edu.sg.ORCID 0000-0002-3697-171X
Yuxin LiuDepartment of Biomedical Engineering (BME), National University of Singapore, Singapore, Singapore. lyx@nus.edu.sg.ORCID 0000-0003-0623-9402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous and in situ detection of biomarkers in biofluids (for example, sweat) can provide critical health data but is limited by biofluid accessibility. Here we report a sensor design that enables in situ detection of solid-state biomarkers ubiquitously present on human skin. We deploy an ionic-electronic bilayer hydrogel to facilitate the sequential dissolution, diffusion and electrochemical reaction of solid-state analytes. We demonstrate continuous monitoring of water-soluble analytes (for example, solid lactate) and water-insoluble analytes (for example, solid cholesterol) with ultralow detection limits of 0.51 and 0.26 nmol cm

Indexed as

BiomarkersEpidermisHydrogelsWearable Electronic DevicesBiosensing TechniquesElectrochemical TechniquesElectronicsHumansBiomarkersHydrogels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.