ArticleEuropean child & adolescent psychiatry2025
Association of preterm birth and birth size status with neurodevelopmental and psychiatric disorders in spontaneous births.
Article in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Prenatal metabolic adversity reprograms insulin-responsive transcription in the developing nucleus accumbens.Molecular metabolism · 2026Article
- Fetal size, gestational age, and cognitive performance at 5 years in term-born children: Four national cohorts' study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- A cross-sectional study on the growth and development of preterm infants during the first year of life in Tibet's Lhasa Region.Medicine · 2026Article
- Risk factors for developmental delays in small for gestational age children at age of 24-36 months.European child & adolescent psychiatry · 2026Article
- Clinical and Sociodemographic Characteristics Associated with Access to Early Intervention Programs for Infants with Prodromes of Autism.Journal of clinical medicine · 2026Article
- Neurodevelopmental risks of late-preterm and early-term births: a population-based study from Finland.BMJ public health · 2026Article
- Associations of prenatal exposure to maternal autoimmune disorders with a wide spectrum of psychiatric and neurodevelopmental disorders in offspring-a nationwide cohort study.Human reproduction open · 2026Article
- Article
- Distinct modifiable risk factors and preventable burdens of preterm birth: a risk-stratified analysis of pregnancies with and without gestational diabetes mellitus.Frontiers in pediatrics · 2026Article
- Preterm Birth and the Emergence of ADHD Symptoms: A Review of Recent Evidence.Medicina (Kaunas, Lithuania) · 2025Review
- Uterus transplantation; first data on neurologic, neuropsychiatric, and physical examination follow-up of children up to 6 years of age.Human reproduction (Oxford, England) · 2025Observational
- Prematurity and Epigenetic Regulation ofBiomedicines · 2025Article
- The Association of Preterm Birth With Autism Spectrum Disorder.Biological psychiatry global open science · 2025Article
- Offspring exposure to Crohn's disease during pregnancy and association with milder psychiatric regulatory disturbances in childhood.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Sequelae of preterm birth over the lifespan: an exploratory analysis of behavioral problems in childhood and increased risk of major depression and anxiety in adulthood from a cohort study.EClinicalMedicine · 2025Article
- The effect of birthweight and gestational age on cognitive function in midlife: the Bogalusa heart study.BMC neurology · 2025Article
- Gestational Age and Cognitive Development in Childhood.JAMA network open · 2025Article
- Association of premature birth and maternal education level on attention deficit hyperactivity disorder in children: A meta-analysis.World journal of psychiatry · 2024Article
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6 authors.
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Abstract
Preterm birth (PTB) or small birth size are risk factors for certain neurodevelopmental disorders. The magnitude of these associations in spontaneous births, and of associations for combined PTB and birth size status on neurodevelopmental and psychiatric disorders is unexplored. We investigated whether PTB and small/large for gestational age (SGA/LGA), separately or combined, in spontaneous births, are associated with a wide spectrum of neurodevelopmental and psychiatric disorders. In this population-based registry cohort study, all singleton spontaneous births in Finland from 1996 to 2014 were followed until 2018 (n = 819 764). We show that PTB across gestational ages, and SGA, were associated with higher risks for anxiety disorders, intellectual disabilities, specific developmental disorders (SDD), autism spectrum disorders (ASD), attention-deficit/hyperactivity disorders (ADHD) and other emotional and behavioural disorders (F98). Most of these associations were not attributed to familial factors. Larger effect sizes were observed with lower gestational ages. Extremely PTB was associated at highest risks with intellectual disabilities (HR, 10.70 [95%CI, 8.69-13.17]) and SDD (HR, 8.91 [95%CI, 8.18-9.71]). Moreover, very preterm birth combined with SGA was associated with a higher risk for SDD (HR, 7.55 [95%CI, 6.61-8.62]) than that of very preterm or SGA birth alone. Conversely, LGA birth lowered the risk for SDD and other emotional and behavioural disorders among individuals born very preterm. In conclusion, PTB along with SGA is associated with higher risks for SDD than one exposure alone, whereas LGA lowers the risks for SDD and other emotional and behavioural disorders in individuals born spontaneously.
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