ArticleScientific reports2024
Quantitative study of the ossification centers of the body of sphenoid bone in the human fetus.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The developing spheno-occipital skull base: developmental variants and embryologic remnants that mimic pathology in children.Pediatric radiology · 2026Review
- The Developing Human Sphenoid Bone: Linking Embryological Development to Adult Morphology.Biology · 2025Review
- Computed Tomography-Based Morphometric Analysis of Ossification Centers of Lesser Wings of Sphenoid Bone in Human Fetuses.Brain sciences · 2025Article
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Authors and funding
3 authors.
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Abstract
The aim of the present study was to examine the growth dynamics of the two ossification centers of the body of sphenoid bone in the human fetus, based on their linear, planar and volumetric parameters. The examinations were carried out on 37 human fetuses of both sexes aged 18-30 weeks of gestation, which had been preserved in 10% neutral formalin solution. Using CT, digital image analysis software, 3D reconstruction and statistical methods, we evaluated the size of the presphenoid and postsphenoid ossification centers. The presphenoid ossification center grew proportionately in sagittal diameter, projection surface area and volume, and logarithmically in transverse diameter. The postsphenoid ossification center increased logarithmically in sagittal diameter, transverse diameter and projection surface area, while its volumetric growth followed proportionately. The numerical findings of the presphenoid and postsphenoid ossification centers may be considered age-specific reference values of potential relevance in monitoring the normal fetal growth and screening for congenital disorders in the fetus. The obtained results may contribute to a better understanding of the growing fetal skeleton, bringing new numerical information regarding its diagnosis and development.
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