Evidence map›Paper›PMID 38866649›Full record

ArticleUltrasound in medicine & biology2024

Anterior Chamber Depth and Lens Thickness Measurements in Pediatric Eyes: Ultrasound Biomicroscopy Versus Immersion A-Scan Ultrasonography.

Taylor Kolosky, Urjita Das, Bhakti Panchal, Sarah Byun, Alexandra Dolgetta, Moran R Levin, Janet L Alexander

Abstract readComparative Study
In one paragraph

Article in Ultrasound in medicine & biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Taylor KoloskyUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Urjita DasUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Bhakti PanchalUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Sarah ByunUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Alexandra DolgettaDepartment of Ophthalmology, Westchester Medical Center, Valhalla, NY, USA.
Moran R LevinDepartment of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Janet L AlexanderDepartment of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: jalexander@som.umaryland.edu.

Funding

Institutional Career Development CoreKL2TR003099 · NCATS · JOHNS HOPKINS UNIVERSITY · PI GEBO, KELLY A · 2019 to 2023
$7.9M
Identification of Anterior Segment Structural Biomarkers in Glaucoma Following Pediatric Cataract Using Ultrasound BiomicroscopyK23EY032525 · NEI · UNIVERSITY OF MARYLAND BALTIMORE · PI ALEXANDER, JANET LEATH · 2022 to 2024
$709k
NCATS NIH HHS KL2 TR003099NEI NIH HHS K23 EY032525
6 · The paper itself

Abstract

objectiveTo compare anterior chamber depth (ACD) and lens thickness (LT) measurements by ultrasound biomicroscopy (UBM), A-scan cross vector (CV) overlay with UBM, and immersion A-scan technique in pediatric eyes.

methodsThis prospective comparative cohort study comprised 43 eyes of 25 pediatric participants (mean age: 2.3±2.2 y). UBM and immersion A-scan biometry were performed prior to dilation and intraocular surgery. ACD and LT were measured by UBM image analysis, A-scan CV UBM overlay, and immersion A-scan technique.

resultsACD and LT measurements obtained using immersion A-scan were significantly greater than with UBM image analysis with mean differences of 0.52 mm and 0.62 mm, respectively (p < 0.001). Immersion A-scan and UBM measurements were moderately correlated (r = 0.70 and 0.64, p < 0.001). ACD and LT measurements obtained using CV overlay were not significantly different than UBM measurements and the values were strongly positively correlated (r = 0.95 and 0.93, p < 0.001).

conclusionImmersion A-scan may overestimate ACD and LT compared to UBM in pediatric patients due to oblique placement of the A-scan probe relative to the optical axis. Supplemental use of UBM and/or CV overlay is indicated to improve measurement accuracy in pediatric patients who cannot reliably fixate due to the ability to confirm proper alignment of the probe with the pupil by visualizing the anterior segment.

Indexed as

Anterior ChamberBiometryLens, CrystallineMicroscopy, AcousticChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleProspective StudiesReproducibility of ResultsSensitivity and SpecificityAnterior chamberA-scanLens thicknessPediatricUltrasound biomicroscopy

Identifiers

PMID38866649
PMCPMC11298292

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