Evidence map›Paper›PMID 38866578›Full record

ArticleBMJ open2024

Assessing the risks for stillbirth in São Paulo, Brazil: protocol for a multidisciplinary case-control study - FetRisks.

Rafael Junqueira Buralli, Zilda Pereira da Silva, Gizelton Pereira Alencar, Gerusa Maria Figueiredo, Mara Sandra Hoshida, Expedito J A Luna, Luciana Duzolina Manfré Pastro, Osmara Alves Dos Santos, Lays Janaina Prazeres Marques, Rodrigo Melim Zerbinati and 10 more

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Rafael Junqueira BuralliDepartamento de Medicina Preventiva, Universidade de Sao Paulo Faculdade de Medicina, Sao Paulo, Brazil rafael.buralli@gmail.com.ORCID 0000-0001-7006-6177
Zilda Pereira da SilvaDepartamento de Epidemiologia, Universidade de Sao Paulo Faculdade de Saude Publica, São Paulo, Brazil.ORCID 0000-0003-4648-113X
Gizelton Pereira AlencarDepartamento de Epidemiologia, Universidade de Sao Paulo Faculdade de Saude Publica, São Paulo, Brazil.ORCID 0000-0002-2354-9050
Gerusa Maria FigueiredoUniversidade de São Paulo Instituto de Medicina Tropical de São Paulo, Sao Paulo, Brazil.
Mara Sandra HoshidaLaboratorio de Investigaçao Medica em Fisiologia Obstetrica (LIM 57), Universidade de São Paulo Hospital das Clínicas, São Paulo, Brazil.ORCID 0000-0003-2232-4631
Expedito J A LunaDepartamento de Medicina Preventiva, Universidade de São Paulo Faculdade de Medicina, São Paulo, Brazil.ORCID 0000-0002-1145-9672
Luciana Duzolina Manfré PastroDepartamento de Medicina Preventiva, Universidade de São Paulo Faculdade de Medicina, São Paulo, Brazil.ORCID 0000-0001-5268-4713
Osmara Alves Dos SantosDepartamento de Medicina Preventiva, Universidade de São Paulo Faculdade de Medicina, São Paulo, Brazil.
Lays Janaina Prazeres MarquesDepartamento de Epidemiologia, Universidade de São Paulo Faculdade de Saude Pública, São Paulo, Brazil.ORCID 0000-0003-4511-4995
Rodrigo Melim ZerbinatiLaboratorio de Virologia (LIM 52), Universidade de São Paulo Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.
Andrés Jimenez Galisteo JuniorLaboratorio de Investigaçao Medica em Protozoologia, Bacteriologia e Resistencia Antimicrobiana (LIM 49), Universidade de Sao Paulo Hospital das Clinicas, São Paulo, Brazil.
Heitor de Andrade JuniorUniversidade de São Paulo Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.
Clarisse M MachadoUniversidade de São Paulo Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.
Luciana Regina MeirelesUniversidade de São Paulo Instituto de Medicina Tropical de São Paulo, São Paulo, Brazil.ORCID 0000-0003-0913-1579
Regina SchultzLaboratorio de Anatomia Patologica, Universidade de Sao Paulo Hospital das Clinicas, São Paulo, Brazil.
Laura Cunha RodriguesLondon School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0001-9008-660X
Rossana Pulcineli Vieira FranciscoLaboratorio de Investigaçao Medica em Fisiologia Obstetrica (LIM 57), Universidade de São Paulo Hospital das Clínicas, São Paulo, Brazil.ORCID 0000-0002-9981-8069
Hillegonda Maria Dutilh NovaesDepartamento de Medicina Preventiva, Universidade de São Paulo Faculdade de Medicina, São Paulo, Brazil.ORCID 0000-0001-9849-0324
Marcia Furquim de AlmeidaDepartamento de Epidemiologia, Universidade de Sao Paulo Faculdade de Saude Publica, São Paulo, Brazil.ORCID 0000-0003-0052-1888
Nelson GouveiaDepartamento de Medicina Preventiva, Universidade de Sao Paulo Faculdade de Medicina, Sao Paulo, Brazil.ORCID 0000-0003-0625-0265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stillbirth is a fundamental component of childhood mortality, but its causes are still insufficiently understood. This study aims to explore stillbirth risk factors by using a multidisciplinary approach to stimulate public policies and protocols to prevent stillbirth, improve maternal care and support bereaved families. METHODS AND ANALYSIS: In this case-control study with stillbirths and live births in 14 public hospitals in São Paulo, mothers are interviewed at hospitals after delivery, and hospital records and prenatal care registries are reviewed. Maternal and umbilical cord blood samples and placentas are collected to analyse angiogenesis and infection biomarkers, and the placenta's anatomopathological exam. Air pollutant exposure is estimated through the participant's residence and work addresses. Traditional and non-invasive autopsies by image-guided histopathology are conducted in a subset of stillbirths. Subsample mothers of cases are interviewed at home 2 months after delivery on how they were dealing with grief. Information contained in the official prenatal care registries of cases and controls is being compiled. Hospital managers are interviewed about the care offered to stillbirth mothers. Data analysis will identify the main risk factors for stillbirth, investigate their interrelations, and evaluate health services care and support for bereaved families. We hope this project will contribute to the understanding of stillbirth's risk factors and related health services in Brazil, providing new knowledge about this central public health problem, contributing to the improvement of public policies and prenatal and puerperal care, helping to prevent stillbirths and improve the healthcare and support for bereaved families. ETHICS AND DISSEMINATION: This study protocol was approved by the Ethics Committee of the Municipal Health Secretary (process no 16509319.0.3012.5551) and of the Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (process no 16509319.0.0000.0068). Results will be communicated to the study participants, policy-makers and the scientific community.

Indexed as

StillbirthBrazilCase-Control StudiesFemaleHumansPlacentaPregnancyPrenatal CareResearch DesignRisk AssessmentRisk Factorscase-control studiesfetal medicinelatin americaprenatal diagnosispublic health

Identifiers

PMID38866578
PMCPMC11177680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.