Evidence map›Paper›PMID 38866557›Full record

ArticleGenes & development2024

Aaron T Crain, Megan B Butler, Christina A Hill, Mai Huynh, Robert K McGinty, Robert J Duronio

Abstract read
In one paragraph

Article in Genes & development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Set2 and H3K36 regulate thebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

6 authors.

Aaron T CrainCurriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599 USA.ORCID 0000-0002-2425-5695
Megan B ButlerDepartment of Biology, University of North Carolina, Chapel Hill, North Carolina 27599 USA.ORCID 0009-0006-0699-8336
Christina A HillIntegrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 USA.ORCID 0009-0004-5147-502X
Mai HuynhLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 USA.
Robert K McGintyLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 USA.ORCID 0000-0001-9641-7350
Robert J DuronioCurriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599 USA; duronio@med.unc.edu.ORCID 0000-0001-6469-6965

Funding

NRSA IN GENETICST32GM007092 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 1985 to 2019
$5.9M
Molecular Mechanisms of Chromatin RecognitionR35GM133498 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Robert McGinty · 2019 to 2026
$3.3M
Epigenetic Control of the Cell Cycle During Animal DevelopmentR35GM145258 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Robert J Duronio · 2022 to 2026
$2.3M
NIGMS NIH HHS R35 GM133498NIGMS NIH HHS R35 GM145258NIGMS NIH HHS T32 GM007092
6 · The paper itself

Abstract

Monomethylation of lysine 20 of histone H4 (H4K20me1) is catalyzed by Set8 and thought to play important roles in many aspects of genome function that are mediated by H4K20me binding proteins. We interrogated this model in a developing animal by comparing in parallel the transcriptomes of

Indexed as

Drosophila melanogasterDrosophila ProteinsHistone-Lysine N-MethyltransferaseHistonesLysineAnimalsGene Expression Regulation, DevelopmentalLarvaMethylationMutationTranscriptomeDrosophila ProteinsHistone-Lysine N-MethyltransferaseHistonesLysinechromatinDrosophila melanogasterepigeneticsgene expressiongenomicsH4K20me1L(3)mbtSet8

Identifiers

PMID38866557
PMCPMC11216177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.